{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:04:42Z","timestamp":1756339482002,"version":"3.44.0"},"reference-count":17,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,12,7]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Adenoid cystic carcinoma (AdCC) of the breast is a rare histological subtype of breast cancer, which usually has a low propensity for metastasis and is associated with a good prognosis. AdCC metastasis to the kidney is rare, with only 29 cases reported in the literature. We report a case of a woman in her 60s with multiple right-sided large cystic-solid renal lesions after a recent diagnosis of marginal zone B-cell lymphoma. The patient previously had T1c N0 breast AdCC, treated with curative intent surgery and adjuvant radiotherapy 10 years prior. She underwent a radical nephrectomy, and histology was confirmed asmetastatic classic AdCC, consistent with the spread from previous AdCC breast cancer. Although she was in remission for 10 years, it is imperative to distinguish between breast AdCC metastasis and primary cystic renal cell carcinoma to be able to formulate an optimal management strategy for these tumours.<\/jats:p>","DOI":"10.1136\/bcr-2024-262550","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T20:20:17Z","timestamp":1736194817000},"page":"e262550","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Unexpected presentation: metastatic adenoid cystic carcinoma (AdCC) of the breast masquerading as a large cystic-solid renal mass"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4298-2981","authenticated-orcid":false,"given":"Benjamin Ngie Xiong","family":"Wong","sequence":"first","affiliation":[{"name":"Department of Surgery, Austin Hospital, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7675-7208","authenticated-orcid":false,"given":"David Chun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology, Peter MacCallum Cancer Centre Division of Cancer Surgery, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Duplessis","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Austin Hospital, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4398-8341","authenticated-orcid":false,"given":"Dixon","family":"Woon","sequence":"additional","affiliation":[{"name":"Department of Urology, Austin Hospital, East Melbourne, Victoria, Australia"},{"name":"Melbourne Urology Care"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,1,6]]},"reference":[{"key":"2025082707410560000_18.1.e262550.1","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1002\/1097-0142(19910901)68:5<1015::AID-CNCR2820680518>3.0.CO;2-Z","article-title":"Adenoid cystic carcinoma of the breast metastatic to the kidney. A clinically symptomatic lesion requiring surgical management","volume":"68","author":"Herzberg","year":"1991","journal-title":"Cancer"},{"key":"2025082707410560000_18.1.e262550.2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4143\/crt.2014.46.1.93","article-title":"Adenoid Cystic Carcinoma of the Breast: A Case Series of Six Patients and Literature Review","volume":"46","author":"Kim","year":"2014","journal-title":"Cancer Res Treat"},{"key":"2025082707410560000_18.1.e262550.3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00428-023-03711-6","article-title":"Adenoid cystic carcinoma metastatic to the kidney: a series of 10 patients emphasizing unilateral presentation and long time interval from primary diagnosis","volume":"484","author":"Akgul","year":"2024","journal-title":"Virchows Arch"},{"key":"2025082707410560000_18.1.e262550.4","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.2214\/AJR.21.25796","article-title":"Bosniak Classification of Cystic Renal Masses Version 2019: Comparison With Version 2005 for Class Distribution, Diagnostic Performance, and Interreader Agreement Using CT and MRI","volume":"217","author":"Park","year":"2021","journal-title":"AJR Am J Roentgenol"},{"key":"2025082707410560000_18.1.e262550.5","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1007\/s00330-016-4631-9","article-title":"Malignancy rates and diagnostic performance of the Bosniak classification for the diagnosis of cystic renal lesions in computed tomography - a systematic review and meta-analysis","volume":"27","author":"Sevcenco","year":"2017","journal-title":"Eur Radiol"},{"key":"2025082707410560000_18.1.e262550.6","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000001911"},{"key":"2025082707410560000_18.1.e262550.7","unstructured":"Geschickter CF . Diseases of the Breast: Diagnosis, Pathology and Treatment. Philadelphia, PA: Lippincott, 1945."},{"key":"2025082707410560000_18.1.e262550.8","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1038\/modpathol.3800483","article-title":"KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome","volume":"18","author":"Azoulay","year":"2005","journal-title":"Mod Pathol"},{"key":"2025082707410560000_18.1.e262550.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2007.03.021"},{"key":"2025082707410560000_18.1.e262550.10","doi-asserted-by":"crossref","first-page":"100006","DOI":"10.1016\/j.modpat.2022.100006","article-title":"Clinicopathologic Predictors of Clinical Outcomes in Mammary Adenoid Cystic Carcinoma: A Multi-institutional Study","volume":"36","author":"Khoury","year":"2023","journal-title":"Mod Pathol"},{"key":"2025082707410560000_18.1.e262550.11","doi-asserted-by":"publisher","DOI":"10.1007\/s002770050556"},{"key":"2025082707410560000_18.1.e262550.12","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ygyno.2014.10.029","article-title":"Risk of second cancers cancer after a first primary breast cancer: a systematic review and meta-analysis","volume":"136","author":"Molina-Montes","year":"2015","journal-title":"Gynecol Oncol"},{"key":"2025082707410560000_18.1.e262550.13","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s10549-021-06465-4","article-title":"Studying the association between breast cancer and renal cell carcinoma","volume":"191","author":"Jazieh","year":"2022","journal-title":"Breast Cancer Res Treat"},{"key":"2025082707410560000_18.1.e262550.14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/0391560321990271","article-title":"Primary renal non-Hodgkin\u2019s lymphoma: A narrative review of literature","volume":"89","author":"Geramizadeh","year":"2022","journal-title":"Urologia"},{"key":"2025082707410560000_18.1.e262550.15","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/ejh.13360","article-title":"Primary renal lymphoma: A population-based analysis using the SEER program (1973-2015)","volume":"104","author":"Taneja","year":"2020","journal-title":"Eur J Haematol"},{"key":"2025082707410560000_18.1.e262550.16","doi-asserted-by":"crossref","DOI":"10.11604\/pamj.2022.42.269.34470","article-title":"Primary diffuse large B-cell lymphoma of the right kidney: a case report","volume":"42","author":"Nasrollahi","year":"2022","journal-title":"Pan Afr Med J"},{"key":"2025082707410560000_18.1.e262550.17","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4103\/ijc.ijc_634_21","article-title":"Primary renal lymphoma masquerading as metastasis in a patient with primary breast cancer and systemic lupus erythematosus","volume":"61","author":"Bhat","year":"2024","journal-title":"Indian J Cancer"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-262550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:41:14Z","timestamp":1756305674000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-262550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,6]]},"published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1136\/bcr-2024-262550"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-262550","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}