{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T01:19:50Z","timestamp":1793755190797,"version":"4.6.1"},"reference-count":10,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"unspecified","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,11,7]]},"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:p>Huntington\u2019s disease (HD) causes progressive neurodegeneration, impairing activities of daily living (ADL). Treatment focuses primarily on symptomatic relief through multidisciplinary approaches. This case report examines the impact of somato-cognitive coordination therapy (SCCT) on ADL in a patient with HD. A woman in her 40s with early-stage HD underwent 22 SCCT sessions using the mediVR KAGURA (mediVR), a virtual reality technology-based medical device over 20 months. Her total functional capacity rating scale improved from 10 to 11 and her Barthel Index improved from 90 to 100 within 3 months, allowing her to continue working. These improvements were sustained for 17 months. Objective measures like the single-leg stance test showed consistent progress. Improved cognitive function and psychiatric well-being were also suggested by the Trail Making Test and a return to hobbies like hiking. SCCT may have the potential to improve ADL and could complement multidisciplinary care strategy for HD patients.<\/jats:p>","DOI":"10.1136\/bcr-2024-262695","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T20:31:26Z","timestamp":1733344286000},"page":"e262695","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of somato-cognitive coordination therapy on activities of daily living in a patient with Huntington\u2019s disease"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5353-2882","authenticated-orcid":false,"given":"Keito","family":"Shinmoto","sequence":"first","affiliation":[{"name":"Department of Neurology and Clinical Rehabilitation, mediVR Rehabilitation Center Tokyo, Chuo-ku, Tokyo, Japan"},{"name":"Office of Research and Academia-Government-Community Collaboration, Headquarters for Open Innovation, Department of Academia-Government-Industry Collaboration, Biodesign Division, Hiroshima University, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Torikai","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Rehabilitation, mediVR Rehabilitation Center Osaka, Toyonaka, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Rehabilitation, mediVR Rehabilitation Center Osaka, Toyonaka, Osaka, Japan"},{"name":"Centre for Community-Based Healthcare Research and Education, Shimane University Faculty of Medicine, Izumo, Shimane, 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body trunk-balance training in a sitting position improves persistent postural-perceptual dizziness: proof of concept","volume":"19","author":"Yamaguchi","year":"2022","journal-title":"J Neuroeng Rehabil"},{"key":"2025082723075768000_17.12.e262695.9","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41586-023-05964-2","article-title":"A somato-cognitive action network alternates with effector regions in motor cortex","volume":"617","author":"Gordon","year":"2023","journal-title":"Nature New Biol"},{"key":"2025082723075768000_17.12.e262695.10","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.390"}],"container-title":["BMJ Case 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