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We experienced a case involving a late adolescent with acne vulgaris who had been treated with minocycline for more than 2 years, leading to the development of drug-induced lupus, attributed to minocycline. This resulted in multiple clinic and emergency department visits and extensive and expensive workups, including an invasive procedure. A collaboration between antibiotic stewardship activities and patient-centred medication reviews, followed by personalised deprescribing, could effectively mitigate inappropriate antibiotic prescriptions for non-infectious dermatologic conditions.<\/jats:p>","DOI":"10.1136\/bcr-2024-262755","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T10:06:07Z","timestamp":1734516367000},"page":"e262755","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Minocycline-induced lupus"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7167-270X","authenticated-orcid":false,"given":"Shinya","family":"Hasegawa","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven M","family":"Craig","sequence":"additional","affiliation":[{"name":"Rheumatology, Iowa Arthritis and Osteoporosis Center, Urbandale, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5953-3704","authenticated-orcid":false,"given":"Hiroyuki","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"key":"2025082708531843000_17.12.e262755.1","unstructured":"Centers for Disease Control and Prevention . 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