{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:05:27Z","timestamp":1790737527015,"version":"4.1.0"},"reference-count":5,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,1,25]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>Treatment-induced neuropathy of diabetes (TIND) is an under-recognised complication that arises after rapid glycaemic control in diabetic patients. It presents with acute autonomic dysfunction and\/or neuropathic pain resulting from small fibre nerve damage. This case involves a woman in her 50s with type 2 diabetes who transitioned from oral hypoglycaemic agents to insulin therapy, leading to a significant drop in HbA1c from 10% to 7.2% within the last 3 months. She presented with painful sensations, orthostatic hypotension and syncope. A diagnostic workup revealed peripheral nerve and autonomic dysfunction. Symptomatic treatment, including pregabalin and intravenous fluids, led to symptom resolution. This case highlights the importance of recognising TIND in patients with rapid glycaemic control to prevent unnecessary interventions. Awareness and appropriate management, including gradual glycaemic correction, can significantly improve patient outcomes.<\/jats:p>","DOI":"10.1136\/bcr-2024-262818","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T12:47:16Z","timestamp":1739278036000},"page":"e262818","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Treatment-induced neuropathy of diabetes (TIND): a hidden complication in diabetes management"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2687-3529","authenticated-orcid":false,"given":"Akash","family":"Paruthi","sequence":"first","affiliation":[{"name":"Internal Medicine, Sawai Man Singh Medical College, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohith","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,2,11]]},"reference":[{"key":"2025082800082935000_18.2.e262818.1","first-page":"1254","article-title":"Treatment-induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes","volume":"133","author":"Gibbons","year":"2010","journal-title":"Brain"},{"key":"2025082800082935000_18.2.e262818.2","doi-asserted-by":"publisher","DOI":"10.2337\/cd21-as01"},{"key":"2025082800082935000_18.2.e262818.3","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12097"},{"key":"2025082800082935000_18.2.e262818.4","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-023600","article-title":"Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials","volume":"9","author":"Onakpoya","year":"2019","journal-title":"BMJ Open"},{"key":"2025082800082935000_18.2.e262818.5","first-page":"616","article-title":"Treatment-Induced Neuropathy of Diabetes: An Acute, Reversible Complication of Diabetes","volume":"15","author":"Gibbons","year":"2015","journal-title":"Curr Diab Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-262818","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:08:40Z","timestamp":1756364920000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-262818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":5,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,11]]},"published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1136\/bcr-2024-262818"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-262818","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]}}}