{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T06:10:13Z","timestamp":1765174213545,"version":"3.46.0"},"reference-count":19,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,10,2]]},"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Primary bladder perivascular epithelioid cell tumours (PEComas) are rare tumours that typically present in the third or fourth decade of life. Radiological and histopathological findings play a crucial role in establishing the diagnosis, and treatment is primarily based on surgical excision. We present the case of a primary bladder PEComa in an early adolescent male presenting with macroscopic haematuria and a hypervascular bladder mass. These peculiar symptoms should prompt consideration of the rare diagnosis of PEComa, even in paediatric patients.<\/jats:p>","DOI":"10.1136\/bcr-2024-262972","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T06:05:21Z","timestamp":1765173921000},"page":"e262972","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primary bladder perivascular epithelioid cell tumour in an early adolescent"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6732-4243","authenticated-orcid":false,"given":"Francesca","family":"Gigola","sequence":"first","affiliation":[{"name":"Paediatric Surgery Unit, Universit\u00e9 Paris-Saclay, Assistance Publique-H\u00f4pitaux de Paris, Hopital Bicetre, Le Kremlin-Bicetre, \u00cele-de-France, France"},{"name":"Postgraduate school of Paediatric Surgery, University of Florence, Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Mussini","sequence":"additional","affiliation":[{"name":"Pathology department, Assistance Publique-H\u00f4pitaux de Paris, Hopital Bicetre, Le Kremlin-Bic\u00eatre, \u00cele-de-France, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geraldine","family":"H\u00e9ry","sequence":"additional","affiliation":[{"name":"Paediatric Surgery Unit, Universit\u00e9 Paris-Saclay, Assistance Publique-H\u00f4pitaux de Paris, Hopital Bicetre, Le Kremlin-Bicetre, \u00cele-de-France, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Rigaud","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Campus, Universit\u00e9 Paris-Saclay, Villejuif, France, Gustave Roussy, Villejuif, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3487-3745","authenticated-orcid":false,"given":"Florent","family":"Gu\u00e9rin","sequence":"additional","affiliation":[{"name":"Paediatric Surgery Unit, Universit\u00e9 Paris-Saclay, Assistance Publique-H\u00f4pitaux de Paris, Hopital Bicetre, Le Kremlin-Bicetre, \u00cele-de-France, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,12,7]]},"reference":[{"key":"2025120722051441000_18.12.e262972.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199203000-00013"},{"key":"2025120722051441000_18.12.e262972.2","doi-asserted-by":"crossref","first-page":"e79","DOI":"10.1016\/j.clgc.2016.08.010","article-title":"Primary Perivascular Epithelioid Cell Tumor (PEComa) of the Bladder: A Case Report With 2-Years of Follow-Up and Review of Current Literature","volume":"15","author":"Creti","year":"2017","journal-title":"Clin Genitourin Cancer"},{"key":"2025120722051441000_18.12.e262972.3","doi-asserted-by":"crossref","DOI":"10.1186\/1746-1596-7-183","article-title":"Perivascular epithelioid cell neoplasm of the urinary bladder in an adolescent: a case report and review of the literature","volume":"7","author":"Yin","year":"2012","journal-title":"Diagn Pathol"},{"key":"2025120722051441000_18.12.e262972.4","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-019-09836-y"},{"key":"2025120722051441000_18.12.e262972.5","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1016\/j.asjsur.2022.06.154","article-title":"Diagnosis and treatment of urachal perivascular epithelioid cell neoplasm: A rare case report","volume":"45","author":"Kou","year":"2022","journal-title":"Asian J Surg"},{"key":"2025120722051441000_18.12.e262972.6","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-007-0378-7"},{"key":"2025120722051441000_18.12.e262972.7","doi-asserted-by":"crossref","first-page":"1324193","DOI":"10.3389\/fonc.2024.1324193","article-title":"Case report: Urachal perivascular epithelioid cell tumor","volume":"14","author":"Liu","year":"2024","journal-title":"Front Oncol"},{"key":"2025120722051441000_18.12.e262972.8","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1007\/s00261-022-03568-4","article-title":"Mesenchymal neoplasms of the urinary bladder: a comprehensive review with focus on cross-sectional imaging findings","volume":"47","author":"Balasubramanya","year":"2022","journal-title":"Abdom Radiol"},{"key":"2025120722051441000_18.12.e262972.9","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jpedsurg.2008.10.040","article-title":"Conservative surgery plus brachytherapy treatment for boys with prostate and\/or bladder neck rhabdomyosarcoma: a single team experience","volume":"44","author":"Martelli","year":"2009","journal-title":"J Pediatr Surg"},{"key":"2025120722051441000_18.12.e262972.10","doi-asserted-by":"crossref","first-page":"372","DOI":"10.4235\/agmr.22.0138","article-title":"Rapidly Progressive Malignant Pelvic Perivascular Epithelioid Cell Neoplasm (PEComa) Associated with Eggerthella lenta Bloodstream Infection","volume":"26","author":"Cacciatore","year":"2022","journal-title":"Ann Geriatr Med Res"},{"key":"2025120722051441000_18.12.e262972.11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/PAS.0000000000001592","article-title":"Histopathologic Characterization of Bladder Perivascular Epithelioid Cell Neoplasms (PEComa): A Series of 11 Cases With a Subset Having TFE3 Rearrangements","volume":"45","author":"Neumann","year":"2021","journal-title":"Am J Surg Pathol"},{"key":"2025120722051441000_18.12.e262972.12","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318293729d"},{"key":"2025120722051441000_18.12.e262972.13","doi-asserted-by":"publisher","DOI":"10.1097\/rct.0b013e318031912f"},{"key":"2025120722051441000_18.12.e262972.14","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/1752-1947-8-227","article-title":"Bone metastases from bladder perivascular epithelioid cell tumor \u2013 an unusual localization of a rare tumor: a case report","volume":"8","author":"Palleschi","year":"2014","journal-title":"J Med Case Reports"},{"key":"2025120722051441000_18.12.e262972.15","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01728"},{"key":"2025120722051441000_18.12.e262972.16","doi-asserted-by":"crossref","first-page":"615","DOI":"10.2147\/CMAR.S351284","article-title":"Management Strategies for Adults with Locally Advanced, Unresectable or Metastatic Malignant Perivascular Epithelioid Cell Tumor (PEComa): Challenges and Solutions","volume":"15","author":"Czarnecka","year":"2023","journal-title":"CMAR"},{"key":"2025120722051441000_18.12.e262972.17","doi-asserted-by":"crossref","first-page":"582087","DOI":"10.3389\/fonc.2020.582087","article-title":"Case Report: Gastrointestinal PEComa With TFE3 Rearrangement Treated With Anti-VEGFR TKI Apatinib","volume":"10","author":"Xu","year":"2020","journal-title":"Front Oncol"},{"key":"2025120722051441000_18.12.e262972.18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbo.2020.100336","article-title":"Primary perivascular epithelioid cell tumor (PEComa) in bone: A review of the literature and a case arising in the humerus with multiple metastases","volume":"26","author":"Zhong","year":"2021","journal-title":"J Bone Oncol"},{"key":"2025120722051441000_18.12.e262972.19","doi-asserted-by":"crossref","DOI":"10.1186\/s13014-018-0974-5","article-title":"Unresectable hepatic PEComa: a rare malignancy treated with stereotactic body radiation therapy (SBRT) followed by complete resection","volume":"13","author":"Kirste","year":"2018","journal-title":"Radiat Oncol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-262972","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T06:05:23Z","timestamp":1765173923000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-262972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":19,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,7]]},"published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1136\/bcr-2024-262972"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-262972","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]}}}