{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:40:09Z","timestamp":1756280409999,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,1,16]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>Fetus in fetu (FIF) is a rare anomaly of embryogenesis in which a malformed parasitic twin is found within the body of the normally developed host twin. It has a reported incidence of 1 per 500\u2009000 births with a 2:1 male predominance. The authors present a unique case of FIF, where autopsy investigation played a pivotal role in identifying this exceptionally rare anomaly, rarely documented in the literature. A primigravida woman in her early 20s was diagnosed with FIF at 13+3 weeks of gestation. She opted for medical termination of her pregnancy. The postmortem examination confirmed the diagnosis of FIF. Malformations in both fetuses, namely, partial urorectal septum malformation in the parasitic twin and heterotaxy syndrome in the host twin, were unmasked by fetal autopsy.<\/jats:p>\n               <jats:p>The significance of autopsy examination in FIF cases is underscored by our case, as it facilitates the diagnosis of this rare entity and the reporting of congenital anomalies in the aforementioned.<\/jats:p>","DOI":"10.1136\/bcr-2024-263111","type":"journal-article","created":{"date-parts":[[2025,2,16]],"date-time":"2025-02-16T06:10:47Z","timestamp":1739686247000},"page":"e263111","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Fetus in fetu: the importance of autopsy in uncovering hidden abnormalities"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9217-1055","authenticated-orcid":false,"given":"Umamaheswari","family":"Gurusamy","sequence":"first","affiliation":[{"name":"Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, TamilNadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7198-2553","authenticated-orcid":false,"given":"Vartika","family":"Goel","sequence":"additional","affiliation":[{"name":"Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, TamilNadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyama","family":"Devadasan","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Ambady Fetal and Maternal Care Centre, Thrissur, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,2,16]]},"reference":[{"key":"2025082700121045000_18.2.e263111.1","first-page":"20230001","article-title":"Antenatally detected fetus in fetu case report","volume":"9","author":"Puranik","year":"2023","journal-title":"BJR Case Rep"},{"key":"2025082700121045000_18.2.e263111.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.01.061"},{"key":"2025082700121045000_18.2.e263111.3","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1007\/s00404-019-05211-y","article-title":"Fetus-in-fetu: a rare condition that requires common rules for its definition","volume":"302","author":"Barakat","year":"2020","journal-title":"Arch Gynecol Obstet"},{"key":"2025082700121045000_18.2.e263111.4","unstructured":"Gonzalez-Crussi F . Atlas of tumor pathology. In: Extragonadal teratomas. Washington DC: Armed Forces Institute of Pathology, 1982."},{"key":"2025082700121045000_18.2.e263111.5","doi-asserted-by":"crossref","unstructured":"Jihwaprani MC , Mousa AA , Mohamed AA , et al . Fetus-in-Fetu: A Differential Diagnosis of Neonatal Fetiform Encysted Abdominal Mass. Cureus 2023;15. doi:10.7759\/cureus.33725","DOI":"10.7759\/cureus.33725"},{"key":"2025082700121045000_18.2.e263111.6","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.epsc.2015.10.006","article-title":"Fetus in fetu: Review of the literature over the past 15 years","volume":"3","author":"Prescher","year":"2015","journal-title":"J Pediatr Surg Case Rep"},{"key":"2025082700121045000_18.2.e263111.7","doi-asserted-by":"publisher","DOI":"10.1002\/ca.1079"},{"key":"2025082700121045000_18.2.e263111.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(97)90567-4"},{"key":"2025082700121045000_18.2.e263111.9","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s12262-012-0745-8","article-title":"Fetus-in-Fetu: Mimicking as Teratoma on Antenatal Ultrasound","volume":"75","author":"Kehal","year":"2013","journal-title":"Indian J Surg"},{"key":"2025082700121045000_18.2.e263111.10","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1080\/14767058.2018.1449207","article-title":"Fetus-in-fetu: two case reports","volume":"32","author":"Ruffo","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"key":"2025082700121045000_18.2.e263111.11","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1186\/s12884-019-2612-0","article-title":"Prenatal diagnosis of a 'living' oropharyngeal fetus in fetu: a case report","volume":"19","author":"Wang","year":"2019","journal-title":"BMC Pregnancy Childbirth"},{"key":"2025082700121045000_18.2.e263111.12","first-page":"e1","article-title":"Image of the Month: Meconium Peritonitis with Pseudocyst-A Spot Diagnosis in Newborns","volume":"8","author":"Ascherl","year":"2020","journal-title":"E J P Surg Rep"},{"key":"2025082700121045000_18.2.e263111.13","unstructured":"Philippe J , Kay C , Patricia D . Fetus in fetu. Article Published on May 31, 2002;"},{"key":"2025082700121045000_18.2.e263111.14","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1177\/1742271X19836259","article-title":"Pre natal evaluation of heterotaxy syndrome by fetal echocardiography and correlating with autopsy","volume":"27","author":"Routhu","year":"2019","journal-title":"Ultrasound"},{"key":"2025082700121045000_18.2.e263111.15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/cga.12149","article-title":"Spectrum of urorectal septum malformation sequence","volume":"56","author":"Shah","year":"2016","journal-title":"Congenit Anom (Kyoto)"},{"key":"2025082700121045000_18.2.e263111.16","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1007\/s00246-021-02656-4","article-title":"High Familial Recurrence of Congenital Heart Defects in Laterality Defects Patients: An Evaluation of 184 Families","volume":"42","author":"Hu","year":"2021","journal-title":"Pediatr Cardiol"},{"key":"2025082700121045000_18.2.e263111.17","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1002\/ajmg.a.35950","article-title":"Recurrence of urorectal septum malformation sequence spectrum anomalies in siblings: time to explore the genetics","volume":"161A","author":"Aggarwal","year":"2013","journal-title":"Am J Med Genet A"},{"key":"2025082700121045000_18.2.e263111.18","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1002\/ajmg.a.31362","article-title":"Origin and mechanisms of formation of fetus-in-fetu: two cases with genotype and methylation analyses","volume":"140","author":"Miura","year":"2006","journal-title":"Am J Med Genet A"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-263111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:12:21Z","timestamp":1756278741000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-263111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,16]]},"published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1136\/bcr-2024-263111"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-263111","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,2]]}}}