{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:37:40Z","timestamp":1787017060923,"version":"build-2736575974"},"reference-count":17,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:00:00Z","timestamp":1734048000000},"content-version":"unspecified","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"fonds scientifique cardiovasculaire, Fribourg","award":["2024_17"],"award-info":[{"award-number":["2024_17"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,11,20]]},"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:p>Phaeochromocytomas are rare catecholamine-secreting tumours, usually benign, originating from chromaffin cells of the adrenal glands. Their typical presentation includes the triad of headaches, sweating and tachycardia due to excessive catecholamine release. However, many patients do not exhibit all three symptoms, making diagnosis challenging. A significant proportion of cases (around 40%) are linked to genetic disorders. Cardiac complications, including life-threatening events, are common.<\/jats:p>\n                  <jats:p>This report details the case of a 43-year-old woman presenting with chest pain, headaches and diaphoresis. Initial ECG showed an anterolateral ST-elevation myocardial infarction pattern, but coronary angiography revealed no arterial disease. The left ventricular angiogram indicated apical ballooning. Elevated blood pressure prompted suspicion of phaeochromocytoma, which was confirmed through positive metanephrine tests.<\/jats:p>\n                  <jats:p>The tumour, located in the right adrenal gland, was successfully removed laparoscopically, and pathological examination confirmed the diagnosis.<\/jats:p>\n                  <jats:p>Phaeochromocytoma should be suspected in patients with unexplained myocardial infarction, labile hypertension and normal coronary arteries, as beta-blockers can be harmful if used in untreated cases.<\/jats:p>","DOI":"10.1136\/bcr-2024-263311","type":"journal-article","created":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T20:35:17Z","timestamp":1734294917000},"page":"e263311","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Phaeochromocytoma mimicking acute ST-elevation myocardial infarction"],"prefix":"10.1136","volume":"17","author":[{"given":"Theresa","family":"Ackfeld","sequence":"first","affiliation":[{"name":"General Internal Medicine, Universit\u00e9 de Fribourg Facult\u00e9 de m\u00e9decine, Fribourg, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadrien","family":"Beuret","sequence":"additional","affiliation":[{"name":"Cardiology, Universit\u00e9 de Fribourg Facult\u00e9 de m\u00e9decine, Fribourg, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Mosar","sequence":"additional","affiliation":[{"name":"General Internal Medicine, Universit\u00e9 de Fribourg Facult\u00e9 de m\u00e9decine, Fribourg, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8337-4053","authenticated-orcid":false,"given":"Stephane","family":"Cook","sequence":"additional","affiliation":[{"name":"Cardiology, Universit\u00e9 de Fribourg Facult\u00e9 de m\u00e9decine, Fribourg, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,12,15]]},"reference":[{"key":"2025082703453991000_17.12.e263311.1","unstructured":"Lloyd RV , Osamura R , Kl\u00f6ppel G , et al . WHO classification of tumours. 4th edn. 10. Lyon: IARC Press, 2017."},{"key":"2025082703453991000_17.12.e263311.2","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-18-0085"},{"key":"2025082703453991000_17.12.e263311.3","first-page":"354","article-title":"Prevalence of clinically unsuspected pheochromocytoma. Review of a 50-year autopsy series","volume":"56","author":"Sutton","year":"1981","journal-title":"Mayo Clin Proc"},{"key":"2025082703453991000_17.12.e263311.4","first-page":"120","article-title":"Adrenal incidentaloma or epinephroma and review of the literature. Differential diagnosis of adrenal incidentaloma","volume":"82","author":"Farrugia","year":"2016","journal-title":"Khirurgiia (Sofiia)"},{"key":"2025082703453991000_17.12.e263311.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.02.007"},{"key":"2025082703453991000_17.12.e263311.6","doi-asserted-by":"crossref","unstructured":"Young WF . Adrenal medulla, catecholamines, and pheochromocytoma. In: Goldman L , Schafer AI , eds. Goldman\u2019s Cecil medicine. 24th edn. Philadelphia, 2012: 1470\u20135.","DOI":"10.1016\/B978-1-4377-1604-7.00235-9"},{"key":"2025082703453991000_17.12.e263311.7","unstructured":"Neumann H . Pheochromocytoma. In: Jameson JL , Fauci A , Kasper D , et al , eds. Harrison\u2019s principles of internal medicine. 20th edn. New York, NY, 2018."},{"key":"2025082703453991000_17.12.e263311.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.09.022"},{"key":"2025082703453991000_17.12.e263311.9","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32834a4ce9"},{"key":"2025082703453991000_17.12.e263311.10","first-page":"e72","article-title":"A case of paroxysmal pheochromocytoma concurrent with coronary artery aneurysm presenting as acute coronary syndrome","volume":"8","author":"Moriwaki","year":"2013","journal-title":"J Cardiol Cases"},{"key":"2025082703453991000_17.12.e263311.11","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-1498"},{"key":"2025082703453991000_17.12.e263311.12","doi-asserted-by":"publisher","DOI":"10.1515\/enr-2017-0018"},{"key":"2025082703453991000_17.12.e263311.13","doi-asserted-by":"crossref","first-page":"3088","DOI":"10.1210\/clinem\/dgaa441","article-title":"Approach to the Patient: Perioperative Management of the Patient with Pheochromocytoma or Sympathetic Paraganglioma","volume":"105","author":"Berends","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"2025082703453991000_17.12.e263311.14","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2015.39"},{"key":"2025082703453991000_17.12.e263311.15","article-title":"Pathophysiology of stress cardiomyopathy: A comprehensive literature review","volume":"82","author":"Al Houri","year":"2022","journal-title":"Ann Med Surg (Lond)"},{"key":"2025082703453991000_17.12.e263311.16","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232012262","article-title":"Molecular Mechanisms of Takotsubo Syndrome","volume":"23","author":"Couch","year":"2022","journal-title":"Int J Mol Sci"},{"key":"2025082703453991000_17.12.e263311.17","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000617"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-263311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:46:01Z","timestamp":1756291561000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-263311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":17,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,15]]},"published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1136\/bcr-2024-263311"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-263311","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]}}}