{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:40:06Z","timestamp":1756327206677,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,2,26]]},"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Tarlov cysts or perineural cysts are extradural cerebrospinal fluid (CSF)-filled sacs commonly found in the sacral spine. Their clinical significance is often underestimated due to diagnostic challenges. This case report describes a female patient presenting with rectal pain, coccydynia, dyspareunia and urinary symptoms. Initial imaging revealed a 4\u2009cm Tarlov cyst at the S3 level, along with two smaller cysts between the S1 and S2 vertebrae. Despite significant symptomatology, spontaneous regression of the S3 cyst was observed within 4\u2009months, leading to the cancellation of a scheduled surgical intervention. This case is notable as spontaneous regression of Tarlov cysts is exceedingly rare, with only one prior documented instance. This report suggests a potential dynamic process involving CSF flow in and out of the cyst which may contribute to the growth of the lesion but also, in rare cases, to a decrease in size up to complete disappearance.<\/jats:p>","DOI":"10.1136\/bcr-2024-263396","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T09:41:02Z","timestamp":1741945262000},"page":"e263396","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous regression of a sacral Tarlov cyst"],"prefix":"10.1136","volume":"18","author":[{"given":"Davide","family":"Boeris","sequence":"first","affiliation":[{"name":"Neurosurgery, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Petrella","sequence":"additional","affiliation":[{"name":"Neurosurgery, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Bursi","sequence":"additional","affiliation":[{"name":"Neurosurgery, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Cenzato","sequence":"additional","affiliation":[{"name":"Neurosurgery, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"2025082713113954000_18.3.e263396.1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.4184\/asj.2014.8.2.202","article-title":"Cervical perineural cyst masquerading as a cervical spinal tumor","volume":"8","author":"Joshi","year":"2014","journal-title":"Asian Spine J"},{"key":"2025082713113954000_18.3.e263396.2","doi-asserted-by":"crossref","DOI":"10.1164\/rccm.201908-1574IM","article-title":"A Case of Thoracic 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