{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:42:46Z","timestamp":1756381366583,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,4,19]]},"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Catamenial dermatosis is a rare condition characterised by premenstrual flares of cutaneous and mucosal lesions due to hormonal fluctuations. We present a patient with recurrent oral ulcers beginning before menstruation, starting as painful vesicles that progressed to ulcers and resolved postmenses. Histopathology revealed a subepidermal cleft with inflammatory infiltrates, and viral cytopathic effects were absent. Based on the cyclical pattern and exclusion of other causes, catamenial erythema multiforme was diagnosed. Acute episodes were managed with corticosteroids and antiviral therapy, while continuous ovulation suppression using combined contraceptive pills effectively prevented recurrence. During 6\u2009months of follow-up, no lesions recurred, underscoring the role of ovulation suppression in breaking the cycle of hormonal triggers. This case highlights the multifaceted management of catamenial erythema multiforme, with hormonal modulation as a key strategy for recurrence prevention in this condition potentially linked to Herpes simplex virus reactivation.<\/jats:p>","DOI":"10.1136\/bcr-2024-263416","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T09:55:15Z","timestamp":1745661315000},"page":"e263416","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Management of catamenial oral erythema multiforme: ovulation suppression for recurrence prevention"],"prefix":"10.1136","volume":"18","author":[{"given":"Avantika","family":"Gupta","sequence":"first","affiliation":[{"name":"All India Institute of Medical Science Bhopal, Bhopal, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0951-867X","authenticated-orcid":false,"given":"Satish","family":"Choudhury","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Science Bhopal, Bhopal, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerene","family":"Mathews","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Science Bhopal, Bhopal, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ujjawal","family":"Khurana","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Science Bhopal, Bhopal, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,4,26]]},"reference":[{"key":"2025082804091089000_18.4.e263416.1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/ced.12333","article-title":"Catamenial dermatoses: has anyone ever considered prostaglandins?","volume":"39","author":"Verdolini","year":"2014","journal-title":"Clin Exp Dermatol"},{"key":"2025082804091089000_18.4.e263416.2","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ad.2017.11.016","article-title":"Respuesta de la dermatitis autoinmune por progesterona al acetato de ulipristal","volume":"110","author":"Oscoz-Jaime","year":"2019","journal-title":"Actas Dermo-Sifiliogr\u00e1ficas"},{"key":"2025082804091089000_18.4.e263416.3","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.ijwd.2019.09.008","article-title":"Catamenial dermatoses associated with autoimmune, inflammatory, and systemic diseases: A systematic review,","volume":"5","author":"Zachary","year":"2019","journal-title":"Int J Womens Dermatol"},{"key":"2025082804091089000_18.4.e263416.4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12070-011-0169-y","article-title":"Erythema multiforme-oral variant: case report and review of literature","volume":"63","author":"Kohli","year":"2011","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"2025082804091089000_18.4.e263416.5","first-page":"23","article-title":"A case of catamenial erythema multiforme major successfully treated with goserelin","volume":"2023","author":"Tyack","year":"2023","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"2025082804091089000_18.4.e263416.6","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jaip.2017.01.019","article-title":"Progestogen Hypersensitivity: Heterogeneous Manifestations with a Common Trigger","volume":"5","author":"Buchheit","year":"2017","journal-title":"J Allergy Clin Immunol Pract"},{"key":"2025082804091089000_18.4.e263416.7","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.anai.2018.11.016","article-title":"Cyclical hypersensitivity, anaphylaxis, and related hormonal reaction","volume":"122","author":"Lavery","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"key":"2025082804091089000_18.4.e263416.8","unstructured":"Hafsi W , Badri T . Erythema multiforme. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2024. Available: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470259\/"},{"key":"2025082804091089000_18.4.e263416.9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1001\/jamadermatol.2018.3973","article-title":"Herpes-Associated Erythema Multiforme","volume":"155","author":"Hashemi","year":"2019","journal-title":"JAMA Dermatol"},{"key":"2025082804091089000_18.4.e263416.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(02)00062-1"},{"key":"2025082804091089000_18.4.e263416.11","first-page":"6692495","article-title":"Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment","volume":"2021","author":"Mtiri","year":"2021","journal-title":"Case Rep Dent"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-263416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:09:17Z","timestamp":1756379357000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-263416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,26]]},"published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1136\/bcr-2024-263416"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-263416","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,4]]}}}