{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:35:27Z","timestamp":1783038927324,"version":"3.54.6"},"reference-count":39,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"unspecified","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,12,25]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Meningioma regression after progestin treatment interruption is already established. Zoely is a combined oral contraceptive including oestradiol and progestin (nomegestrol acetate). The effect of combined oestrogen with nomegestrol acetate on meningioma is currently unknown. We report the case of a woman in her early 50s under Zoely for 5 years who was diagnosed with a large petroclival meningioma. After cessation of Zoely, the patient showed clinical improvement and shrinkage of the tumour volume from 27.22 cm<jats:sup>3<\/jats:sup> to 20.54 cm<jats:sup>3<\/jats:sup> in 6 months. This is probably the first report of spontaneous meningioma regression after Zoely interruption.<\/jats:p>","DOI":"10.1136\/bcr-2024-263529","type":"journal-article","created":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T20:50:44Z","timestamp":1737319844000},"page":"e263529","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Petroclival meningioma regression after combined oestrogen and nomegestrol acetate interruption"],"prefix":"10.1136","volume":"18","author":[{"given":"Julie","family":"Lebeau","sequence":"first","affiliation":[{"name":"CHU de Li\u00e8ge, Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Deprez","sequence":"additional","affiliation":[{"name":"Radiodiagnostics, CHU de Li\u00e8ge, Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axelle","family":"Pintiaux","sequence":"additional","affiliation":[{"name":"Gynaecology 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