{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:40:12Z","timestamp":1756377612998,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,1,20]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA) osteomyelitis of the maxilla is a rare condition in paediatric patients, with limited evidence available for optimal treatment protocols. We present the case of a paediatric patient in the early childhood age group with post-traumatic maxillary osteomyelitis caused by MRSA. The child developed facial swelling following trauma, and imaging revealed maxillary sinus wall thickening and bone erosions. After initial treatment with analgesics, the swelling persisted, leading to surgical intervention and microbiological analysis confirming MRSA infection. The patient was treated with intravenous linezolid and amikacin for 5\u2009days, followed by 8\u2009weeks of oral linezolid. One year post-treatment, the child remained healthy with no recurrence. This case highlights the importance of early diagnosis, tailored antibiotic therapy and conservative surgical management to ensure positive outcomes in paediatric maxillary osteomyelitis cases. Further research is needed to establish standardised treatment protocols for facial osteomyelitis in children.<\/jats:p>","DOI":"10.1136\/bcr-2024-263580","type":"journal-article","created":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T08:40:58Z","timestamp":1738140058000},"page":"e263580","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Maxillary MRSA osteomyelitis in a paediatric patient: non-surgical management"],"prefix":"10.1136","volume":"18","author":[{"given":"Deepti","family":"Vepakomma","sequence":"first","affiliation":[{"name":"Paediatric Surgery, All India Institute of Medical Sciences Mangalagiri, Mangalagiri, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shikha","family":"Yadav","sequence":"additional","affiliation":[{"name":"Dentistry, All India Institute of Medical Sciences Mangalagiri, Mangalagiri, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,1,29]]},"reference":[{"key":"2025082803173226000_18.1.e263580.1","doi-asserted-by":"crossref","first-page":"196","DOI":"10.17796\/1053-4625-43.3.9","article-title":"Pediatric Maxillary Osteomyelitis: A Case Report of a Rare Entity","volume":"43","author":"Wehl","year":"2019","journal-title":"J Clin Pediatr Dent"},{"key":"2025082803173226000_18.1.e263580.2","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1186\/s12887-021-03031-1","article-title":"Osteomyelitis in Immunocompromised children and neonates, a case series","volume":"21","author":"Foong","year":"2021","journal-title":"BMC Pediatr"},{"key":"2025082803173226000_18.1.e263580.3","doi-asserted-by":"crossref","DOI":"10.5001\/omj.2022.22","article-title":"Prevalence of Methicillin-resistant Staphylococcus Aureus in India: A Systematic Review and Meta-analysis","volume":"37","author":"Patil","year":"2022","journal-title":"Oman Med J"},{"key":"2025082803173226000_18.1.e263580.4","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/s12663-021-01607-z","article-title":"Osteomyelitis of Maxilla: A Rare Presentation Yet Not So Rare","volume":"21","author":"Lata","year":"2022","journal-title":"J Maxillofac Oral Surg"},{"key":"2025082803173226000_18.1.e263580.5","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1053\/joms.2003.50110","article-title":"Primary chronic osteomyelitis in childhood and adolescence: A retrospective analysis of 11 cases and review of the literature","volume":"61","author":"Eyrich","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"2025082803173226000_18.1.e263580.6","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s12519-020-00359-z","article-title":"Acute infectious osteomyelitis in children: new treatment strategies for an old enemy","volume":"16","author":"Congedi","year":"2020","journal-title":"World J Pediatr"},{"key":"2025082803173226000_18.1.e263580.7","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2021-244141","article-title":"Methicillin-resistant Staphylococcus aureus (MRSA)-associated juvenile osteomyelitis of mandible: a rare variant","volume":"14","author":"Chacko","year":"2021","journal-title":"BMJ Case Rep"},{"key":"2025082803173226000_18.1.e263580.8","unstructured":"Heggie AA . Juvenile mandibular chronic osteomyelitis: a distinct clinical entity n.d."},{"key":"2025082803173226000_18.1.e263580.9","doi-asserted-by":"crossref","unstructured":"Berglund C , Ekstr\u00f6mer K , Abtahi J . Primary Chronic Osteomyelitis of the Jaws in Children: An Update on Pathophysiology, Radiological Findings, Treatment Strategies, and Prospective Analysis of Two Cases. Case Rep Dent 2015. doi:10.1155\/2015\/152717","DOI":"10.1155\/2015\/152717"},{"key":"2025082803173226000_18.1.e263580.10","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s12663-012-0374-6","article-title":"Guidelines of the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections: As Applied to Oral and Maxillofacial Clinical Practice","volume":"12","author":"Bhargava","year":"2013","journal-title":"J Maxillofac Oral Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-263580","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:17:37Z","timestamp":1756376257000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-263580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,29]]},"published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1136\/bcr-2024-263580"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-263580","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}