{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T01:24:13Z","timestamp":1793064253361,"version":"4.5.0"},"reference-count":13,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"unspecified","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2024,12,18]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>A woman in her mid-70s presented with worsening dyspnoea, cough and fatigue initially treated for pneumonia. Despite antibiotics, her condition deteriorated, prompting further investigation. Medical history included previous breast implants, the latter of which had ruptured years earlier and was subsequently removed prior to the current presentation. Imaging revealed bilateral lung consolidations and lymphadenopathy. Bronchoalveolar lavage indicated macrophagic alveolitis, while biopsies showed chronic inflammation and the presence of silicone. Diagnosis of chronic pulmonary silicone embolism was made, a rare condition linked to the migration of silicone particles into the lungs, causing inflammation. Treatment involved corticosteroids, leading to symptom resolution. This case highlights the diagnostic challenges of silicone pneumonitis, which can manifest years after implant rupture and removal. Clinicians should be aware of this condition to avoid misdiagnosis and delayed treatment, as symptoms may persist even after implant removal due to irreversible lung fibrosis.<\/jats:p>","DOI":"10.1136\/bcr-2024-263676","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T23:45:30Z","timestamp":1737503130000},"page":"e263676","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Chronic pulmonary silicone embolism after breast implant rupture: an underdiagnosed cause of acute fibrinous and organizing pneumonia?"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5306-0402","authenticated-orcid":false,"given":"Catia","family":"Vieira Gomes","sequence":"first","affiliation":[{"name":"Pneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland"},{"name":"Universit\u00e9 de Gen\u00e8ve, Geneve, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Coquoz","sequence":"additional","affiliation":[{"name":"Pneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"Vervier","sequence":"additional","affiliation":[{"name":"Pneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Yerly","sequence":"additional","affiliation":[{"name":"Pathology, Centre Hospitalier du Valais Romand, Sion, Valais, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Olivier","family":"Bridevaux","sequence":"additional","affiliation":[{"name":"Pneumology, Centre Hospitalier du Valais Romand, Sion, Switzerland"},{"name":"Universit\u00e9 de Gen\u00e8ve, Geneve, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,1,21]]},"reference":[{"key":"2025082700305941000_18.1.e263676.1","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2987072","article-title":"Chronic Pulmonary Silicone Embolism from Breast Augmentation Is Not a Common Finding in Explanted Lungs","volume":"2018","author":"Singh","year":"2018","journal-title":"Pulm Med"},{"key":"2025082700305941000_18.1.e263676.2","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2019-229470","article-title":"Pulmonary fibrosis and embolism secondary to silicon implant leak","volume":"12","author":"Azeem","year":"2019","journal-title":"BMJ Case Rep"},{"key":"2025082700305941000_18.1.e263676.3","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1111\/his.12518","article-title":"Chronic silicone embolism syndrome due to PIP breast implant leakage \u2013 a new entity?","volume":"66","author":"Gopinath","year":"2015","journal-title":"Histopathology"},{"key":"2025082700305941000_18.1.e263676.4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1513\/AnnalsATS.201509-575LE","article-title":"Chronic Pulmonary Silicone Embolism Related to Saline Breast Implants","volume":"13","author":"Arora","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"2025082700305941000_18.1.e263676.5","doi-asserted-by":"crossref","first-page":"e208","DOI":"10.1378\/chest.14-0761","article-title":"Increasing pulmonary infiltrates in a 72-year-old woman with metastatic breast cancer","volume":"146","author":"Bois","year":"2014","journal-title":"Chest"},{"key":"2025082700305941000_18.1.e263676.6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s11845-009-0369-6","article-title":"Pneumonitis caused by silicone gel following breast implant rupture","volume":"179","author":"Paredes Vila","year":"2010","journal-title":"Ir J Med Sci"},{"key":"2025082700305941000_18.1.e263676.7","unstructured":"(ISAPS) ISoAPS . 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