{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:26:18Z","timestamp":1790619978315,"version":"4.1.0"},"reference-count":12,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,5,21]]},"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:p>Lymphangiosarcoma, or Stewart-Treves syndrome, is a rare and aggressive malignancy. It is associated with poor prognosis due to its high risk of recurrence and metastasis. This case report highlights the surgical challenges faced in managing lymphangiosarcoma.<\/jats:p>\n               <jats:p>We present a case of a woman in her 60s who underwent modified radical mastectomy and adjuvant therapy for breast carcinoma. She developed lymphangiosarcoma of the upper limb and underwent limb disarticulation. 6 months later, she presented with recurrent angiosarcoma at the amputation site. A wide local excision was performed, followed by reconstruction with a free anterolateral thigh flap.<\/jats:p>","DOI":"10.1136\/bcr-2024-264152","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T23:45:21Z","timestamp":1749599121000},"page":"e264152","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Challenges in managing Stewart-Treves Syndrome: navigating complexities in recurrent lymphangiosarcoma"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9490-039X","authenticated-orcid":false,"given":"Tanvi","family":"Rao","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harshavardhan Kushal","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlsen Bernard","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"2025082723292358000_18.6.e264152.1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6690726"},{"key":"2025082723292358000_18.6.e264152.2","doi-asserted-by":"crossref","first-page":"378","DOI":"10.4274\/ejbh.galenos.2020.5741","article-title":"Stewart-Treves Syndrome: A Rare But Aggressive Complication of Breast Cancer-Related Lymphedema","volume":"17","author":"Borman","year":"2021","journal-title":"Eur J Breast Health"},{"key":"2025082723292358000_18.6.e264152.3","doi-asserted-by":"crossref","unstructured":"Hsu A , Matera R , Dizon DS . Stewart-Treves syndrome: a rapidly fatal complication of breast cancer treatment. 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