{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:10:04Z","timestamp":1756321804798,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,2,15]]},"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Acquired fat replacement of the pancreatic body and tail is a rare condition that differs from congenital agenesis. A female patient in her 50s presented with a multilocular serous cystic neoplasm located in the pancreatic head extending into the body, accompanied by fat replacement in the pancreatic body and tail. The patient underwent pancreaticoduodenectomy (PD) without remnant pancreatic reconstruction, as the pancreatic duct could not be identified. Postoperatively, no complications occurred, including pancreatic fistula, and endocrine function remained intact, with no diabetes treatment required at the 1-year follow-up. Histopathology confirmed the diagnosis of serous cystadenoma with preserved Langerhans islets within the fat-replaced pancreatic tissue. This case emphasises the potential of preserving endocrine function and preventing complications through PD without reconstruction in cases involving extensive fat replacement.<\/jats:p>","DOI":"10.1136\/bcr-2024-264560","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T16:40:40Z","timestamp":1741020040000},"page":"e264560","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Serous cystadenoma with fat replacement of the pancreatic body and tail with pancreaticoduodenectomy without pancreatic reconstruction followed by preserved pancreatic endocrine function"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9294-9066","authenticated-orcid":false,"given":"Hideki","family":"Mori","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Nakagami Hospital, Okinawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Surgery, Okinawa Prefectural Nanbu Medical Center & Childrens Medical Center, Shimajiri District, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"2025082711483338000_18.3.e264560.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-003-1250-4"},{"key":"2025082711483338000_18.3.e264560.2","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1097\/00004728-200011000-00014","article-title":"Fat replacement with absence of acinar and ductal structure in the pancreatic body and tail","volume":"24","author":"Park","year":"2000","journal-title":"J Comput Assist Tomogr"},{"key":"2025082711483338000_18.3.e264560.3","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.5833\/jjgs.43.1258","article-title":"A Case of Fatty Replacement of Pancreatic Body and Tail Successfully Underwent Pancreatoduodenectomy without Pancreatic Reconstruction Followed by Adequate Control of Diabetes Mellitus","volume":"43","author":"Matsukawa","year":"2010","journal-title":"Jpn J Gastroenterol Surg"},{"key":"2025082711483338000_18.3.e264560.4","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5833\/jjgs.2023.0036","article-title":"Multiple Neuroendocrine Tumors with Fat Replacement of the Pancreatic Body and Tail Treated with Pancreaticoduodenectomy without Pancreaticojejunostomy: A Case Report","volume":"57","author":"Ishihara","year":"2024","journal-title":"Jpn J Gastroenterol Surg"},{"key":"2025082711483338000_18.3.e264560.5","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.3919\/jjsa.78.2525","article-title":"A Case of a Pancreatic Neuroendocrine Tumor with Intraductal Growth and Fat Replacement in the Distal Pancreas","volume":"78","author":"Takahashi","year":"2017","journal-title":"Nihon Rinsho Geka Gakkai Zasshi"},{"key":"2025082711483338000_18.3.e264560.6","doi-asserted-by":"publisher","DOI":"10.1007\/s005950070050"},{"key":"2025082711483338000_18.3.e264560.7","doi-asserted-by":"crossref","first-page":"181","DOI":"10.5833\/jjgs.37.181","article-title":"A Resected Case of Pancreatic Head Cancer with Fatty Replacement of Panceatic Body and Tail","volume":"37","author":"Yamada","year":"2004","journal-title":"Jpn J Gastroenterol Surg"},{"key":"2025082711483338000_18.3.e264560.8","doi-asserted-by":"crossref","first-page":"480","DOI":"10.5833\/jjgs.2020.0059","article-title":"Pancreaticoduodenectomy with Non-Reconstruction of the Remnant Pancreas in Patients with Fat Replacement of the Pancreatic Tail: A Report of Two Cases","volume":"54","author":"Abe","year":"2021","journal-title":"Jpn J Gastroenterol Surg"},{"key":"2025082711483338000_18.3.e264560.9","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1002\/ags3.12795","article-title":"Low incidence of pancreatic fistula and well-preserved endocrine function with non-reconstructed small remnant pancreas after pancreaticoduodenectomy","volume":"8","author":"Miyashita","year":"2024","journal-title":"Ann Gastroenterol Surg"},{"key":"2025082711483338000_18.3.e264560.10","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1097\/00004728-199211000-00017","article-title":"Agenesis of the dorsal pancreas","volume":"16","author":"Soler","year":"1992","journal-title":"J Comput Assist Tomogr"},{"key":"2025082711483338000_18.3.e264560.11","article-title":"Agenesis of the Dorsal Pancreas: A Rare Cause of Diabetes and Recurrent Upper Abdominal Pain","volume":"15","author":"Lalchandani","year":"2023","journal-title":"Cureus"},{"key":"2025082711483338000_18.3.e264560.12","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/BF02385705","article-title":"Histometric analysis of the distal pancreas in pancreatic head cancer","volume":"27","author":"Yamaguchi","year":"1997","journal-title":"Surg Today"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-264560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:48:46Z","timestamp":1756320526000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-264560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":12,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,3,3]]},"published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1136\/bcr-2024-264560"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-264560","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,3]]}}}