{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:40:02Z","timestamp":1756366802064,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"unspecified","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,2,22]]},"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Aortic root thrombosis (ART) is a rare but serious complication following the placement of continuous-flow left ventricular assist devices (CF-LVAD). We present the case of a patient with idiopathic non-ischaemic cardiomyopathy who developed a non-ST elevation myocardial infarction (NSTEMI) secondary to ART after CF-LVAD placement. The patient was treated conservatively with antiplatelet therapy and increased international normalized ratio (INR) goal with resolution of thrombus on repeat imaging. ART may be an under-recognised complication in patients with CF-LVAD. Stasis of blood at the aortic root in patients with CF-LVAD may contribute to the development of ART. Management of these patients presenting with myocardial infarction should be individualised by using a multidisciplinary team approach. Our case report suggests conservative management of NSTEMI secondary to ART in patients with CF-LVAD with antiplatelet therapy and an increased INR goal as a reasonable treatment approach.<\/jats:p>","DOI":"10.1136\/bcr-2024-264624","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T07:07:41Z","timestamp":1743145661000},"page":"e264624","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Non-ST elevation myocardial infarction from aortic root thrombus after LVAD placement"],"prefix":"10.1136","volume":"18","author":[{"given":"Daniel","family":"Holtz","sequence":"first","affiliation":[{"name":"Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhythm","family":"Vasudeva","sequence":"additional","affiliation":[{"name":"Cardiology, The University of Kansas Medical Center, Kansas City, Kansas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Zorn","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Surgery, The University of Kansas Medical Center, Kansas City, Kansas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zubair","family":"Shah","sequence":"additional","affiliation":[{"name":"Cardiology, The University of Kansas Medical Center, Kansas City, Kansas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4115-6189","authenticated-orcid":false,"given":"Tarun","family":"Dalia","sequence":"additional","affiliation":[{"name":"Cardiology, The University of Kansas Medical Center, Kansas City, Kansas, 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