{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T15:53:40Z","timestamp":1777046020527,"version":"3.51.4"},"reference-count":13,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,4,11]]},"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>The prevalence of macular telangiectasia type 2 (MacTel-2) is often underestimated. However, recent studies indicate that it could be as high as 0.1% in individuals aged \u226540 years. MacTel-2 typically presents with subtle clinical signs such as right-angled venules, intraretinal crystalline deposits and minimal pigmentary changes. Although the presence of large pigment clumps is uncommon, they can significantly affect visual function as the disease progresses.<\/jats:p>\n                  <jats:p>We present two cases of bilateral large pigment clumps secondary to parafoveal telangiectasia and discuss their clinical and diagnostic features.<\/jats:p>","DOI":"10.1136\/bcr-2024-264784","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:30:15Z","timestamp":1777041015000},"page":"e264784","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Large pigment clumps in macula secondary to parafoveal telangiectasia"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6861-2957","authenticated-orcid":false,"given":"Sanghamitra","family":"Kanungo","sequence":"first","affiliation":[{"name":"Ophthalmology, Kar Vision Eye Hospital, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6975-4437","authenticated-orcid":false,"given":"Shradha","family":"Pattnaik","sequence":"additional","affiliation":[{"name":"Ophthalmology, Kar Vision Eye Hospital, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok Kumar","family":"Nanda","sequence":"additional","affiliation":[{"name":"Kar Vision Eye Hospital, Bhubaneswar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalatendu","family":"Satpathy","sequence":"additional","affiliation":[{"name":"Ophthalmology, Kar Vision Eye Hospital, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"2026042407300763000_19.4.e264784.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.02.013"},{"key":"2026042407300763000_19.4.e264784.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(93)31447-8"},{"key":"2026042407300763000_19.4.e264784.3","first-page":"215","article-title":"Tumors and Related Lesions of the Pigmented Epithelium","volume":"6","author":"Shields","year":"2017","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"key":"2026042407300763000_19.4.e264784.4","doi-asserted-by":"crossref","unstructured":"Enghelberg M , Kaifee S . 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GMS Ophthalmol Cases 2021;11. doi:10.3205\/oc000176"},{"key":"2026042407300763000_19.4.e264784.10","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1038\/s41433-022-02260-7","article-title":"Hyperpigmented epiretinal membrane in macular telangiectasia type 2: imaging characteristics and correlation with transretinal pigment migration","volume":"37","author":"Cabral","year":"2023","journal-title":"Eye (Lond)"},{"key":"2026042407300763000_19.4.e264784.11","doi-asserted-by":"crossref","unstructured":"Venkatesh R , Reddy NG , Mishra P , et al . Spectral domain OCT features in type 2 macular telangiectasia (type 2 MacTel): its relevance with clinical staging and visual acuity. Int J Retina Vitreous 2022;8. doi:10.1186\/s40942-022-00378-0","DOI":"10.1186\/s40942-022-00378-0"},{"key":"2026042407300763000_19.4.e264784.12","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-313364"},{"key":"2026042407300763000_19.4.e264784.13","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00417-013-2491-4","article-title":"Diagnosis of subretinal neovascularization associated with idiopathic juxtafoveal retinal telangiectasia - fluorescein angiography versus spectral-domain optical coherence tomography","volume":"252","author":"Chhablani","year":"2014","journal-title":"Graefes Arch Clin Exp Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-264784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:30:17Z","timestamp":1777041017000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-264784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4,24]]},"published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1136\/bcr-2024-264784"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-264784","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}