{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T10:43:46Z","timestamp":1761907426884,"version":"build-2065373602"},"reference-count":18,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"unspecified","delay-in-days":29,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,10,11]]},"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>\n                    Central skull base osteomyelitis is a rare, life-threatening condition that can present with vague symptoms and may be missed on initial imaging. We describe a man in his 30s who presented to the emergency department with rapidly progressive neck pain and elevated inflammatory markers. CT imaging was normal, but MRI revealed right occipital condyle osteomyelitis. Blood cultures grew methicillin-resistant\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    , with the source determined to be from his upper and lower limb furunculosis. Despite appropriate antibiotics, he developed cranial nerve deficits and hearing loss. This case highlights the limitations of CT and the importance of early MRI in suspected central skull base osteomyelitis to avoid diagnostic delay and reduce complications.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2024-264788","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T10:40:15Z","timestamp":1761907215000},"page":"e264788","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["CT-negative central skull base osteomyelitis diagnosed on MRI in the emergency department"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6729-4968","authenticated-orcid":false,"given":"Maurice","family":"Wu","sequence":"first","affiliation":[{"name":"Queensland Health, Brisbane, Queensland, Australia"},{"name":"The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Department of Emergency Medicine, Ipswich Hospital, Ipswich, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4744-3944","authenticated-orcid":false,"given":"Benjamin","family":"Powell","sequence":"additional","affiliation":[{"name":"Queensland Health, Brisbane, Queensland, Australia"},{"name":"The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Department of Emergency Medicine, Ipswich Hospital, Ipswich, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Newman","sequence":"additional","affiliation":[{"name":"Queensland Health, Brisbane, Queensland, Australia"},{"name":"The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Department of Emergency Medicine, Ipswich Hospital, Ipswich, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"2025103103400733000_18.10.e264788.1","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-019-01110-w"},{"key":"2025103103400733000_18.10.e264788.2","doi-asserted-by":"crossref","DOI":"10.1016\/j.idcr.2020.e00930","article-title":"Central skull base osteomyelitis secondary to invasive aspergillus sphenoid sinusitis presenting with isolated 12th nerve palsy","volume":"22","author":"Radhakrishnan","year":"2020","journal-title":"IDCases"},{"key":"2025103103400733000_18.10.e264788.3","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24440"},{"key":"2025103103400733000_18.10.e264788.4","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06576-6"},{"key":"2025103103400733000_18.10.e264788.5","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2021200046"},{"key":"2025103103400733000_18.10.e264788.6","doi-asserted-by":"publisher","DOI":"10.4103\/ajns.AJNS_90_17"},{"key":"2025103103400733000_18.10.e264788.7","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3390\/tropicalmed8050254","article-title":"Atypical Skull-Base Osteomyelitis: Comprehensive Review and Multidisciplinary Management Viewpoints","volume":"8","author":"Urban\u010di\u010d","year":"2023","journal-title":"TropicalMed"},{"key":"2025103103400733000_18.10.e264788.8","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A7015"},{"key":"2025103103400733000_18.10.e264788.9","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofae614","article-title":"Central Skull Base Osteomyelitis in Queensland, Australia, 2010-2020","volume":"11","author":"Eustace","year":"2024","journal-title":"Open Forum Infect Dis"},{"key":"2025103103400733000_18.10.e264788.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.03.024"},{"key":"2025103103400733000_18.10.e264788.11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/lary.30161","article-title":"Facial Paralysis in Skull Base Osteomyelitis - Comparison of Surgical and Nonsurgical Management","volume":"133","author":"Freeman","year":"2023","journal-title":"Laryngoscope"},{"key":"2025103103400733000_18.10.e264788.12","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1080\/02688697.2019.1699905","article-title":"Clinical profiling and management outcome of atypical skull base osteomyelitis","volume":"34","author":"Singh","year":"2020","journal-title":"Br J Neurosurg"},{"key":"2025103103400733000_18.10.e264788.13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1214160"},{"key":"2025103103400733000_18.10.e264788.14","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s00256-021-03807-7","article-title":"MRI nomenclature for musculoskeletal infection","volume":"50","author":"Alaia","year":"2021","journal-title":"Skeletal Radiol"},{"key":"2025103103400733000_18.10.e264788.15","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s10143-020-01254-x","article-title":"Skull base osteomyelitis: clinical and radiologic analysis of a rare and multifaceted pathological entity","volume":"44","author":"Schreiber","year":"2021","journal-title":"Neurosurg Rev"},{"key":"2025103103400733000_18.10.e264788.16","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.nic.2009.06.001","article-title":"Imaging of the central skull base","volume":"19","author":"Borges","year":"2009","journal-title":"Neuroimaging Clin N Am"},{"key":"2025103103400733000_18.10.e264788.17","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2013.08.004"},{"key":"2025103103400733000_18.10.e264788.18","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2237"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2024-264788","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T10:40:16Z","timestamp":1761907216000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2024-264788"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":18,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025,10,31]]},"published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1136\/bcr-2024-264788"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2024-264788","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}