{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:40:06Z","timestamp":1756316406145,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,3,18]]},"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:p>Congenital dengue is seen in endemic areas during monsoon seasons. The clinical manifestations can vary from an asymptomatic newborn to mild symptoms like fever and rash to severe manifestations like shock and bleeding. The neurological manifestations of congenital dengue are uncommon compared with older children. The described symptoms\/complications in the literature include congenital birth defects such as microcephaly, encephalitis and intraventricular haemorrhage. Apnoea as a manifestation of dengue has not yet been described in the literature. Here, we discuss a newborn baby with congenital dengue who had recurrent apnoea with positive NS1 antigen in cerebrospinal fluid.<\/jats:p>","DOI":"10.1136\/bcr-2025-264799","type":"journal-article","created":{"date-parts":[[2025,5,11]],"date-time":"2025-05-11T07:25:16Z","timestamp":1746948316000},"page":"e264799","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent apnoea: a neurological manifestation of congenital dengue"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8355-4927","authenticated-orcid":false,"given":"Rajarajan","family":"Paulpandian","sequence":"first","affiliation":[{"name":"Neonatology, Sri Ramachandra Medical College and Research Institute, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1487-836X","authenticated-orcid":false,"given":"Prakash","family":"Amboiram","sequence":"additional","affiliation":[{"name":"Neonatology, Sri Ramachandra Medical College and Research Institute, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8132-9574","authenticated-orcid":false,"given":"Umamaheswari","family":"Balakrishnan","sequence":"additional","affiliation":[{"name":"Neonatology, Sri Ramachandra Medical College and Research Institute, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sowmya","family":"Devaram","sequence":"additional","affiliation":[{"name":"Neonatology, Sri Ramachandra Medical College and Research Institute, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,5,11]]},"reference":[{"key":"2025082710152797000_18.5.e264799.1","doi-asserted-by":"publisher","DOI":"10.1139\/cjm-2020-0572"},{"key":"2025082710152797000_18.5.e264799.2","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0140-6736(24)01542-3","article-title":"Dengue: the threat to health now and in the future","volume":"404","year":"2024","journal-title":"The Lancet"},{"key":"2025082710152797000_18.5.e264799.3","doi-asserted-by":"crossref","first-page":"396","DOI":"10.4269\/ajtmh.24-0387","article-title":"Exposure to Dengue Virus During Pregnancy: Incidence and Impact on Maternal and Child Outcomes","volume":"112","author":"Smith","year":"2025","journal-title":"Am J Trop Med Hyg"},{"key":"2025082710152797000_18.5.e264799.4","article-title":"A Narrative Review of Maternal and Perinatal Outcomes of Dengue in Pregnancy","volume":"15","author":"Ahuja","year":"2023","journal-title":"Cureus"},{"key":"2025082710152797000_18.5.e264799.5","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1177\/09732179231151746","article-title":"Perinatal Transmission of Dengue Infection in a Neonate Presenting as Dengue Shock Syndrome","volume":"37","author":"Pachauri","year":"2023","journal-title":"Journal of Neonatology"},{"key":"2025082710152797000_18.5.e264799.6","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.68654"},{"key":"2025082710152797000_18.5.e264799.7","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/s12098-021-03791-9","article-title":"Dengue Encephalitis in a Newborn","volume":"88","author":"Kalane","year":"2021","journal-title":"Indian J Pediatr"},{"key":"2025082710152797000_18.5.e264799.8","doi-asserted-by":"crossref","first-page":"158","DOI":"10.5005\/jp-journals-11002-0066","article-title":"Neurological Manifestations of Perinatal Dengue","volume":"2","author":"Singh","year":"2023","journal-title":"Newborn (Clarksville)"},{"key":"2025082710152797000_18.5.e264799.9","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70150-9"},{"key":"2025082710152797000_18.5.e264799.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2006.05.068"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-264799","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:15:37Z","timestamp":1756314937000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-264799"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,5,11]]},"published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1136\/bcr-2025-264799"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-264799","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,5]]}}}