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Younger children with MRS are at high risk of nasogastric feeding dependency and additional chronic feeding challenges due to the cumulative impacts of disease flares during the period when feeding skills and interest in foods are first developed. We present a case of a boy in early childhood who presented multiple times over a 4\u2009month period with predominant symptoms of recurrent unilateral facial swelling and significantly reduced oral intake and who was eventually diagnosed with MRS.<\/jats:p>","DOI":"10.1136\/bcr-2025-264924","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T10:30:12Z","timestamp":1758796212000},"page":"e264924","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Melkersson\u2013Rosenthal syndrome: recurrent facial swelling and food refusal"],"prefix":"10.1136","volume":"18","author":[{"given":"Xanthea","family":"Dewez","sequence":"first","affiliation":[{"name":"General Medicine, Royal Children\u2019s Hospital Melbourne Department of General Medicine, Parkville, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitaa","family":"Eapen","sequence":"additional","affiliation":[{"name":"General Medicine, Royal Children\u2019s Hospital Melbourne Department of General Medicine, Parkville, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafsah","family":"Brown","sequence":"additional","affiliation":[{"name":"General Medicine, Royal Children\u2019s Hospital Melbourne Department of General Medicine, Parkville, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jye","family":"Gard","sequence":"additional","affiliation":[{"name":"General Medicine, Royal Children\u2019s Hospital Melbourne Department of General Medicine, Parkville, Victoria, Australia"},{"name":"Murdoch Children's Research Institute, Parkville, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"key":"2025092503300499000_18.9.e264924.1","first-page":"388","article-title":"Feeding Problems in Typically Developing Young Children, a Population-Based Study","volume":"8","author":"Sdravou","year":"2021","journal-title":"Children (Basel)"},{"key":"2025092503300499000_18.9.e264924.2","doi-asserted-by":"publisher","DOI":"10.1542\/pir.34-12-549"},{"key":"2025092503300499000_18.9.e264924.3","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1177\/088453360001500608","article-title":"Current Literature: Pediatric Feeding Disorders","volume":"15","author":"Manikam","year":"2000","journal-title":"Nut in Clin Prac"},{"key":"2025092503300499000_18.9.e264924.4","doi-asserted-by":"crossref","first-page":"196","DOI":"10.2174\/1573396314666180515113941","article-title":"A Systematic Review of the Literature of the Three Related Disease Entities Cheilitis Granulomatosa, Orofacial Granulomatosis and Melkersson - 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