{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:10:04Z","timestamp":1756368604199,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,4,7]]},"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Subacute sclerosing panencephalitis (SSPE) is an uncommon, progressive, and deadly brain condition that develops as a late consequence of a measles virus infection in otherwise healthy individuals, especially in children and young adults. Due to a decrease in vaccination adherence, which has been exacerbated by the COVID-19 pandemic, its frequency has increased in recent years.<\/jats:p>\n               <jats:p>A 2-year-old male child, previously normal, presented with regression of attained milestones along with drop attacks, which eventually increased in frequency along with behavioural concerns. On retrospection, he had a history of self-limiting febrile exanthem with similar complaints in his mother. This child was diagnosed with SSPE and managed accordingly.<\/jats:p>\n               <jats:p>To conclude, SSPE can present with a rapidly deteriorating course mimicking acute disseminated encephalomyelitis (ADEM).<\/jats:p>\n               <jats:p>Myoclonic jerks with periodic complexes on EEG along with cerebrospinal fluid IgM for measles antibodies help to delineate from ADEM and avoid immunosuppression, which could be fatal.<\/jats:p>","DOI":"10.1136\/bcr-2025-264946","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T23:35:13Z","timestamp":1744932913000},"page":"e264946","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Subacute sclerosing panencephalitis (SSPE) masquerading as acute disseminated encephalomyelitis (ADEM)"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7244-0492","authenticated-orcid":false,"given":"Vykuntaraju K","family":"Gowda","sequence":"first","affiliation":[{"name":"Paediatric Neurology, Indira Gandhi Institute of Child Health, Bengaluru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viveka Santhosh Reddy","family":"Challa","sequence":"additional","affiliation":[{"name":"Paediatric Neurology, Indira Gandhi Institute of Child Health, Bengaluru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amaresh","family":"Roy","sequence":"additional","affiliation":[{"name":"Paediatric Neurology, Indira Gandhi Institute of Child Health, Bengaluru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amena","family":"Nayyer","sequence":"additional","affiliation":[{"name":"Paediatric Radiology, Indira Gandhi Institute of Child Health, Bengaluru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"2025082800564014000_18.4.e264946.1","doi-asserted-by":"crossref","DOI":"10.1007\/s12098-023-04975-1","article-title":"Subacute Sclerosing Panencephalitis (SSPE): A Wolf in Sheep\u2019s Clothing-Infantile Presentation Masquerading as Autoimmune Encephalitis","volume":"91","author":"Gowda","year":"2024","journal-title":"Indian J Pediatr"},{"key":"2025082800564014000_18.4.e264946.2","first-page":"58","article-title":"Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection","volume":"47","author":"Sim\u015fek","year":"2005","journal-title":"Turk J Pediatr"},{"key":"2025082800564014000_18.4.e264946.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(98)00100-3"},{"key":"2025082800564014000_18.4.e264946.4","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-002-0979-8"},{"key":"2025082800564014000_18.4.e264946.5","unstructured":"Rocke Z , Belyayeva M . Subacute sclerosing panencephalitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2023."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-264946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:56:50Z","timestamp":1756367810000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-264946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":5,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,17]]},"published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1136\/bcr-2025-264946"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-264946","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,4]]}}}