{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:37:45Z","timestamp":1792291065784,"version":"4.4.0"},"reference-count":6,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,5,11]]},"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:p>A man in his early 20s presented with complaints of a throbbing headache for 1\u2009week and blurred vision for 2\u2009weeks. He had been using oral minoxidil tablets (2.5\u2009mg of minoxidil and 10\u2009000 mcg of biotin) two times per day and topical 5% minoxidil for alopecia (hair and beard) during the same period. On examination, both anterior and posterior segment evaluations were within normal limits, except for hyperaemic optic discs in both eyes. He could only read the demo plates on the Ishihara colour vision chart. Given the absence of genetic factors, an adverse drug reaction to minoxidil was suspected. Consequently, both oral and topical minoxidil were discontinued during the initial visit. The vision improved and the achromatopsia resolved after the cessation of minoxidil, without further intervention.<\/jats:p>","DOI":"10.1136\/bcr-2025-265291","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T05:45:19Z","timestamp":1747806319000},"page":"e265291","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Transient vision loss and achromatopsia associated with use of minoxidil"],"prefix":"10.1136","volume":"18","author":[{"given":"Anup Kumar","family":"Sah","sequence":"first","affiliation":[{"name":"Department of Optometry, Trilochan Netralaya School of Optometry, Sambalpur, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitendra","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Department of Optometry, Trilochan Netralaya School of Optometry, Sambalpur, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitaranjan","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Vitreoretina, Trilochan Netralaya, Sambalpur, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0887-1690","authenticated-orcid":false,"given":"Bijnya Birajita","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"2025082701221613000_18.5.e265291.1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/brain\/awg009","article-title":"Migraine can be induced by sildenafil without changes in middle cerebral artery diameter","volume":"126","author":"Kruuse","year":"2003","journal-title":"Brain (Bacau)"},{"key":"2025082701221613000_18.5.e265291.2","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000537911","article-title":"From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female","volume":"15","author":"Pickel","year":"2024","journal-title":"Case Rep Ophthalmol"},{"key":"2025082701221613000_18.5.e265291.3","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.bbrc.2018.09.164","article-title":"Novel effect of sildenafil on hair growth","volume":"505","author":"Choi","year":"2018","journal-title":"Biochem Biophys Res Commun"},{"key":"2025082701221613000_18.5.e265291.4","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines9030291","article-title":"Visual Side Effects Linked to Sildenafil Consumption: An Update","volume":"9","author":"Aus\u00f3","year":"2021","journal-title":"Biomedicines"},{"key":"2025082701221613000_18.5.e265291.5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1001\/jamaophthalmol.2018.4716","article-title":"Association of Transient Colorblindness With Sildenafil and Tadalafil","volume":"137","author":"Rosen","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"2025082701221613000_18.5.e265291.6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/s12886-020-01499-6","article-title":"Minoxidil induced central serous Chorioretinopathy treated with oral Eplerenone - a case report","volume":"20","author":"Venkatesh","year":"2020","journal-title":"BMC Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-265291","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:22:23Z","timestamp":1756282943000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-265291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":6,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,5,21]]},"published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1136\/bcr-2025-265291"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-265291","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]}}}