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Horner\u2019s syndrome is known to result from sympathetic dysfunction from lesions from the hypothalamus to the cervical\/upper thoracic spine and can be seen with brachial plexopathies, but has never been, to our knowledge, described in MMA. This finding is of interest because it may facilitate earlier diagnosis of MMA in isolated upper extremity, lower motor neuron-predominant syndromes, as Horner\u2019s syndrome is not known to complicate ALS.<\/jats:p>","DOI":"10.1136\/bcr-2025-265315","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T12:55:19Z","timestamp":1757076919000},"page":"e265315","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Co-occurrence of ipsilateral partial Horner\u2019s syndrome in a patient with monomelic amyotrophy"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1325-0717","authenticated-orcid":false,"given":"Vincent","family":"LaBarbera","sequence":"first","affiliation":[{"name":"Department of Neurology, Brown University Warren Alpert Medical School, West Warwick, Rhode Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Neurology, Washington University in St Louis, St. Louis, Missouri, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Sachs","sequence":"additional","affiliation":[{"name":"Department of Neurology, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,9,5]]},"reference":[{"key":"2025090505551244000_18.9.e265315.1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.50.3.285"},{"key":"2025090505551244000_18.9.e265315.2","first-page":"2440","article-title":"Neuroelectrophysiological characteristics of Hirayama disease: report of 14 cases","volume":"125","author":"Guo","year":"2012","journal-title":"Chin Med J (Engl)"},{"key":"2025090505551244000_18.9.e265315.3","doi-asserted-by":"publisher","DOI":"10.1002\/mus.22028"},{"key":"2025090505551244000_18.9.e265315.4","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1034\/j.1600-0404.2001.00016.x","article-title":"Sympathetic skin response in monomelic amyotrophy","volume":"104","author":"Gourie-Devi","year":"2001","journal-title":"Acta Neurol Scand"},{"key":"2025090505551244000_18.9.e265315.5","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/jon.12993","article-title":"Autonomic dysfunction in amyotrophic lateral sclerosis: A neurophysiological and neurosonology study","volume":"32","author":"Papadopoulou","year":"2022","journal-title":"J Neuroimaging"},{"key":"2025090505551244000_18.9.e265315.6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/WNP.0000000000000226","article-title":"Sympathetic Skin Response in Amyotrophic Lateral Sclerosis","volume":"33","author":"Hu","year":"2016","journal-title":"J Clin Neurophysiol"},{"key":"2025090505551244000_18.9.e265315.7","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.94993"},{"key":"2025090505551244000_18.9.e265315.8","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.1.120"},{"key":"2025090505551244000_18.9.e265315.9","unstructured":"Merryman J , Varacallo MA . 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