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CT scans of the abdomen and chest showed no evidence of metastatic disease. During the second year of follow-up, a PET-CT was performed and a new active osseous lesion in the skull was identified. Current follow-up guidelines for colorectal carcinoma may not encompass all potential metastatic sites. Incorporating full body PET-CT scans into the follow-up protocol could be beneficial for detecting additional metastatic sites.<\/jats:p>","DOI":"10.1136\/bcr-2025-265319","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T23:25:03Z","timestamp":1746055503000},"page":"e265319","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Unusual skull metastasis in colorectal adenocarcinoma"],"prefix":"10.1136","volume":"18","author":[{"given":"Lisa","family":"De Cubber","sequence":"first","affiliation":[{"name":"Surgery, Zuyderland Medical Center, Sittard-Geleen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9086-9620","authenticated-orcid":false,"given":"Maud Agnes Maria","family":"Vesseur","sequence":"additional","affiliation":[{"name":"Orthopaedics, Zuyderland Medical Center Orthopedics Department, Heerlen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Stoot","sequence":"additional","affiliation":[{"name":"Surgery, Zuyderland Medical Center, Sittard-Geleen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"van Bastelaar","sequence":"additional","affiliation":[{"name":"Surgery, Zuyderland Medical Center, Sittard-Geleen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.1","DOI":"10.3322\/caac.21763"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.2","DOI":"10.1093\/annonc\/mdx224"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.3","DOI":"10.3322\/canjclin.55.2.74"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.4","DOI":"10.1016\/S0140-6736(13)61649-9"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.5","DOI":"10.1001\/jama.2021.0106"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.6","DOI":"10.1007\/s10585-015-9719-0"},{"key":"2025082622500649000_18.4.e265319.7","doi-asserted-by":"crossref","DOI":"10.1038\/srep29765","article-title":"Patterns of metastasis in colon and rectal cancer","volume":"6","author":"Riihim\u00e4ki","year":"2016","journal-title":"Sci Rep"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.8","DOI":"10.5858\/133.10.1539"},{"key":"2025082622500649000_18.4.e265319.9","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/794354","article-title":"Atypical presentation of skull metastasis from rectal adenocarcinoma as an initial symptom of recurrence","volume":"2012","author":"F\u0131rat","year":"2012","journal-title":"Case Rep Med"},{"key":"2025082622500649000_18.4.e265319.10","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1007\/s12262-017-1610-6","article-title":"Colorectal Cancer: Postoperative Follow-up and Surveillance","volume":"79","author":"Godhi","year":"2017","journal-title":"Indian J Surg"},{"key":"2025082622500649000_18.4.e265319.11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.7888\/juoeh.43.433","article-title":"A Case of Ascending Colon Cancer with Skull Metastasis","volume":"43","author":"Toyofuku","year":"2021","journal-title":"J UOEH"},{"doi-asserted-by":"publisher","key":"2025082622500649000_18.4.e265319.12","DOI":"10.1007\/s11060-010-0465-5"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-265319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:50:13Z","timestamp":1756273813000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-265319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,30]]},"published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1136\/bcr-2025-265319"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-265319","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,4]]}}}