{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:10:05Z","timestamp":1756307405892,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,5,7]]},"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:p>Sturge\u2013Weber syndrome (SWS), also known as encephalotrigeminal angiomatosis, is a rare congenital neurocutaneous syndrome characterised by a triad of cutaneous, ocular and central nervous system findings. In the majority of the patients, it manifests as unilateral facial port-wine stain (PWS), which is a capillary malformation frequently affecting the first branch (ophthalmic division) of the trigeminal nerve. The ocular manifestations involve glaucoma and choroidal haemangiomas, whereas intracranial leptomeningeal venous angiomas form part of the central nervous system involvement. There are a few reports of bilateral PWS involving the trigeminal nerve\u2019s ophthalmic and maxillary branches. We hereby report a case of bilateral SWS associated with soft tissue hypertrophy of the lip and trichomegaly.<\/jats:p>","DOI":"10.1136\/bcr-2025-265439","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T05:45:14Z","timestamp":1747806314000},"page":"e265439","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral Sturge\u2013Weber syndrome with soft tissue hypertrophy and trichomegaly"],"prefix":"10.1136","volume":"18","author":[{"given":"Shivangi","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Dermatology, All India Institute of Medical Sciences - Nagpur, Nagpur, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priyanka","family":"Kowe","sequence":"additional","affiliation":[{"name":"Department of Dermatology, All India Institute of Medical Sciences - Nagpur, Nagpur, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3448-371X","authenticated-orcid":false,"given":"Gitesh U","family":"Sawatkar","sequence":"additional","affiliation":[{"name":"Dermatology, All India Institute of Medical Sciences, Nagpur, Nagpur, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"2025082707491836000_18.5.e265439.1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4103\/0974-620X.127937","article-title":"A rare presentation of bilateral Sturge-Weber syndrome","volume":"7","author":"Nema","year":"2014","journal-title":"Oman J Ophthalmol"},{"key":"2025082707491836000_18.5.e265439.2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.pediatrneurol.2011.01.005","article-title":"Clinical outcomes in bilateral Sturge-Weber 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two case reports","volume":"16","author":"Chagas","year":"2017","journal-title":"J Vasc Bras"},{"key":"2025082707491836000_18.5.e265439.10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2147\/VHRM.S358849","article-title":"The Klippel-Tr\u00e9naunay Syndrome in 2022: Unravelling Its Genetic and Molecular Profile and Its Link to the Limb Overgrowth Syndromes","volume":"18","author":"Harnarayan","year":"2022","journal-title":"Vasc Health Risk Manag"},{"key":"2025082707491836000_18.5.e265439.11","doi-asserted-by":"crossref","DOI":"10.1097\/JOVA.0000000000000076","article-title":"Parkes Weber Syndrome: Contribution of the Genotype to the Diagnosis","volume":"4","author":"Andreoti","year":"2023","journal-title":"Journal of Vascular Anomalies"},{"key":"2025082707491836000_18.5.e265439.12","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20092243","article-title":"The Pathogenesis of Port Wine Stain and Sturge Weber Syndrome: Complex Interactions between Genetic Alterations and Aberrant MAPK and PI3K Activation","volume":"20","author":"Nguyen","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2025082707491836000_18.5.e265439.13","doi-asserted-by":"crossref","DOI":"10.1111\/dth.12991","article-title":"CLAPO syndrome: Effective response to treatment with oral rapamycin","volume":"32","author":"Gonz\u00e1lez-Hermosa","year":"2019","journal-title":"Dermatol Ther"},{"key":"2025082707491836000_18.5.e265439.14","article-title":"Presentation and Management of Klippel-Trenaunay Syndrome: A Review of Available Data","volume":"12","author":"Asghar","year":"2020","journal-title":"Cureus"}],"container-title":["BMJ Case 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