{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:10:10Z","timestamp":1756307410663,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,5,25]]},"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:p>Over the past 20 years, breast augmentation has become increasingly popular for enhancing breast size and correcting asymmetry. Saline implants were initially used, followed by silicone implants and autologous fat transfer. However, complications such as infection, implant failure and capsular contracture are common, while rare cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) exist.<\/jats:p>\n               <jats:p>A woman in her 60s with no breast cancer risk factors underwent bilateral augmentation mammoplasty. Her preoperative imaging was unremarkable, and she was advised to regular follow-up but was lost for several years. She later presented with lumps in both breasts. Imaging revealed a benign lesion in the right breast, a malignant lesion in the left, left-sided axillary lymphadenopathy and bilateral implant rupture.<\/jats:p>\n               <jats:p>Although rare, incidental breast cancer in reduction specimens should not be overlooked. While implant-associated malignancies are often lymphoma, other histological subtypes should also be considered.<\/jats:p>","DOI":"10.1136\/bcr-2025-265546","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T04:10:28Z","timestamp":1750133428000},"page":"e265546","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["From cosmetic to critical: breast implant rupture revealing invasive lobular breast carcinoma"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1167-3830","authenticated-orcid":false,"given":"Fatima","family":"Qaiser","sequence":"first","affiliation":[{"name":"Radiology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hina","family":"Pathan","sequence":"additional","affiliation":[{"name":"Radiology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Raza","sequence":"additional","affiliation":[{"name":"Radiology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7827-6854","authenticated-orcid":false,"given":"Anam","family":"Khan","sequence":"additional","affiliation":[{"name":"Radiology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"key":"2025082707275793000_18.6.e265546.1","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000000749"},{"key":"2025082707275793000_18.6.e265546.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2007.03.017"},{"key":"2025082707275793000_18.6.e265546.3","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.7.801"},{"key":"2025082707275793000_18.6.e265546.4","doi-asserted-by":"crossref","first-page":"734","DOI":"10.5999\/aps.2014.41.6.734","article-title":"A retrospective analysis of ruptured breast implants","volume":"41","author":"Baek","year":"2014","journal-title":"Arch Plast Surg"},{"key":"2025082707275793000_18.6.e265546.5","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1093\/asj\/sjad086","article-title":"Silicone Migration From Breast Implants: A Case of Ocular Siliconoma and Literature Review","volume":"43","author":"Montemurro","year":"2023","journal-title":"Aesthet Surg J"},{"key":"2025082707275793000_18.6.e265546.6","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000164470.76432.4f"},{"key":"2025082707275793000_18.6.e265546.7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s00266-016-0689-7","article-title":"Analysis of 109 Consecutive Explanted Breast Implants: Correlation Between Suspected Implant Rupture and Surgical Findings","volume":"40","author":"Maisel Lotan","year":"2016","journal-title":"Aesthetic Plast Surg"},{"key":"2025082707275793000_18.6.e265546.8","doi-asserted-by":"crossref","first-page":"49S","DOI":"10.1097\/01.prs.0000286569.45745.6a","article-title":"The diagnosis of silicone breast implant rupture","volume":"120","author":"Gorczyca","year":"2007","journal-title":"Plast Reconstr Surg"},{"key":"2025082707275793000_18.6.e265546.9","unstructured":"US Food and Drug Administration . Breast implants\u2014certain labeling recommendations to improve patient communication. Food and Drug Administration; 2020."},{"key":"2025082707275793000_18.6.e265546.10","doi-asserted-by":"crossref","DOI":"10.5334\/jbsr.3691","article-title":"A Case of a Giant Siliconoma Mimicking Localized Breast Cancer","volume":"108","author":"Van Boeckel","year":"2024","journal-title":"J Belg Soc Radiol"},{"key":"2025082707275793000_18.6.e265546.11","first-page":"142","article-title":"Breast prothesis leakage and malignant changes of the breast","volume":"24","author":"Al-Lawati","year":"2009","journal-title":"Oman Med J"},{"key":"2025082707275793000_18.6.e265546.12","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1515\/pjs-2016-0026","article-title":"Massive inflammatory reaction following the removal of a ruptured silicone implant masking the invasive breast cancer \u2013 case report and literature review","volume":"88","author":"Nowaczyk","year":"2016","journal-title":"Polish Journal of Surgery"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-265546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:28:04Z","timestamp":1756304884000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-265546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":12,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,6,16]]},"published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1136\/bcr-2025-265546"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-265546","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}