{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:04:53Z","timestamp":1756339493545,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,6,14]]},"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:p>We report a rare case of lead poisoning after taking a dietary supplement which was bought online. A woman in her 60s presented with symptomatic anaemia and hepatitis for 2 weeks. Bone marrow examination showed sideroblastic anaemia and subsequent blood tests confirmed lead poisoning. She was successfully treated with a course of the chelating agent succimer. Further history and investigations showed that she had taken a <jats:italic>Garcinia cambogia<\/jats:italic> (GC)-based multi-ingredients dietary supplement in the form of capsules for weight reduction and that the lead content within the capsules was very high. Our case illustrates that hepatotoxicity can be associated with the use of dietary supplements. Moreover, blood lead levels should be checked when there is associated sideroblastic anaemia.<\/jats:p>","DOI":"10.1136\/bcr-2025-265732","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T14:25:23Z","timestamp":1750775123000},"page":"e265732","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Rare association between hepatotoxicity and sideroblastic anaemia after taking <i>Garcinia cambogia<\/i>-based dietary supplement"],"prefix":"10.1136","volume":"18","author":[{"given":"Kristy","family":"Tang","sequence":"first","affiliation":[{"name":"Medicine, Queen Elizabeth Hosp, Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9940-2568","authenticated-orcid":false,"given":"Chi Yuen","family":"Cheung","sequence":"additional","affiliation":[{"name":"Medicine, Queen Elizabeth Hosp, Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"2025082708053767000_18.6.e265732.1","doi-asserted-by":"crossref","first-page":"6704","DOI":"10.3748\/wjg.v25.i46.6704","article-title":"Severe liver injury due to herbal and dietary supplements and the role of liver transplantation","volume":"25","author":"Grewal","year":"2019","journal-title":"World J Gastroenterol"},{"key":"2025082708053767000_18.6.e265732.2","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/6483605","article-title":"Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature","volume":"2018","author":"Kothadia","year":"2018","journal-title":"Case Reports Hepatol"},{"key":"2025082708053767000_18.6.e265732.3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.5604\/16652681.1184287","article-title":"Acute liver failure associated with Garcinia cambogia use","volume":"15","author":"Corey","year":"2016","journal-title":"Ann Hepatol"},{"key":"2025082708053767000_18.6.e265732.4","article-title":"Acute Hepatitis due to Garcinia Cambogia Extract, an Herbal Weight Loss Supplement","volume":"2018","author":"Sharma","year":"2018","journal-title":"Case Rep Gastrointest Med"},{"key":"2025082708053767000_18.6.e265732.5","doi-asserted-by":"crossref","first-page":"4689","DOI":"10.3748\/wjg.v19.i29.4689","article-title":"Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation","volume":"19","author":"Kim","year":"2013","journal-title":"WJG"},{"key":"2025082708053767000_18.6.e265732.6","doi-asserted-by":"crossref","first-page":"10071","DOI":"10.3748\/wjg.v22.i45.10071","article-title":"Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation","volume":"22","author":"Lunsford","year":"2016","journal-title":"World J Gastroenterol"},{"key":"2025082708053767000_18.6.e265732.7","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.cgh.2013.07.030","article-title":"Herbs and liver injury: a clinical perspective","volume":"12","author":"Rossi","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2025082708053767000_18.6.e265732.8","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.03.006"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-265732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:05:43Z","timestamp":1756307143000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-265732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":8,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,6,24]]},"published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1136\/bcr-2025-265732"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-265732","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}