{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T06:19:00Z","timestamp":1770445140031,"version":"3.49.0"},"reference-count":14,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,7,17]]},"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:p>Stroke is a neurological emergency that can be either ischaemic or haemorrhagic. Hypertensive disorders of pregnancy are an important risk factor for haemorrhagic stroke, while thrombophilia (acquired or congenital) could increase the risk of ischaemic stroke. Pregnancy itself is a thrombogenic condition, and pregnancy-associated conditions like hyperemesis, pre-eclampsia and ovarian hyperstimulation in assisted conception may further increase this risk. Maternal stroke during pregnancy is an infrequent but debilitating condition that can lead to long-term disability and death. Early diagnosis, prompt treatment and multidisciplinary team management are crucial in optimising outcomes in such cases. Here, we discuss a rare presentation of acute ischaemic stroke in an uncomplicated primigravida, its management and impact on pregnancy outcome.<\/jats:p>","DOI":"10.1136\/bcr-2025-265968","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T04:10:25Z","timestamp":1755144625000},"page":"e265968","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Acute ischaemic stroke in pregnancy"],"prefix":"10.1136","volume":"18","author":[{"given":"Ankita","family":"Dadhwal","sequence":"first","affiliation":[{"name":"Obstetrics & Gynaecology, All India Institute of Medical Sciences Bilaspur, Bilaspur, Bilaspur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7800-0076","authenticated-orcid":false,"given":"Harpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynaecology, All India Institute of Medical Sciences Bilaspur, Bilaspur, Bilaspur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Sharma","sequence":"additional","affiliation":[{"name":"Neurology, All India Institute of Medical Sciences Bilaspur, Bilaspur, Bilaspur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chanderdeep","family":"Sharma","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynaecology, All India Institute of Medical Sciences Bilaspur, Bilaspur, Bilaspur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"2025081321101848000_18.8.e265968.1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182009701"},{"key":"2025081321101848000_18.8.e265968.2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000199613.38911.b2"},{"key":"2025081321101848000_18.8.e265968.3","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ncl.2018.09.010","article-title":"Stroke in Pregnancy: An Update","volume":"37","author":"Camargo","year":"2019","journal-title":"Neurol Clin"},{"key":"2025081321101848000_18.8.e265968.4","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31825f287c"},{"key":"2025081321101848000_18.8.e265968.5","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.594523"},{"key":"2025081321101848000_18.8.e265968.6","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1177\/1747493017723271","article-title":"The incidence of pregnancy-related stroke: A systematic review and meta-analysis","volume":"12","author":"Swartz","year":"2017","journal-title":"Int J Stroke"},{"key":"2025081321101848000_18.8.e265968.7","unstructured":"Cunningham FG , Leveno KJ , Bloom SL , et al . Obstetr\u00edcia de Williams-25. McGraw Hill Brasil 2021."},{"key":"2025081321101848000_18.8.e265968.8","first-page":"1183","article-title":"Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study","volume":"21","author":"Fischer-Betz","year":"2012","journal-title":"Lupus (Los Angel)"},{"key":"2025081321101848000_18.8.e265968.9","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000172428.78411.b0"},{"key":"2025081321101848000_18.8.e265968.10","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1177\/1747493018786617","article-title":"Canadian Stroke Best Practice Consensus Statement: Acute Stroke Management during pregnancy","volume":"13","author":"Ladhani","year":"2018","journal-title":"Int J Stroke"},{"key":"2025081321101848000_18.8.e265968.11","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000211"},{"key":"2025081321101848000_18.8.e265968.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.09.070"},{"key":"2025081321101848000_18.8.e265968.13","doi-asserted-by":"crossref","unstructured":"American heart association, American college of cardiology cardiovascular disease in women committee . Maternal stroke: A call for action. 2021. doi:10.1161\/CIRCULATIONAHA.120.051460","DOI":"10.1161\/CIRCULATIONAHA.120.051460"},{"key":"2025081321101848000_18.8.e265968.14","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1177\/1747493017743801","article-title":"Canadian stroke best practice consensus statement: Secondary stroke prevention during pregnancy","volume":"13","author":"Swartz","year":"2018","journal-title":"Int J Stroke"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-265968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T04:10:27Z","timestamp":1755144627000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-265968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":14,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,13]]},"published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1136\/bcr-2025-265968"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-265968","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8]]}}}