{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T13:08:08Z","timestamp":1780664888257,"version":"3.54.1"},"reference-count":15,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,4,8]]},"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>Adenoid cystic carcinoma (ACC) is a rare, slowly growing salivary gland neoplasm distinguished by its versatile phenotype and destructive clinical course. Its underlying aetiology is unclear. It is characterised by a gradual yet infiltrative progression, perineural invasion (PNI), a worse prognosis, late recurrence and distant metastases. ACC is recognised for its unique histological features and susceptibility to PNI.<\/jats:p>\n                  <jats:p>We present a case of a female in her 50s with a history of progressively enlarging swelling in the right palate diagnosed as a \u201chybrid variant of adenoid cystic carcinoma\u201d. Histopathological analysis confirmed the diagnosis, emphasising the need for long-term follow-up given ACC\u2019s propensity for late recurrence and distant spread, particularly to the lungs. For individuals with advanced non-resectable, recurring and\/or metastatic illness, there is currently no viable treatment. But its prevalence impedes the advancement of additional studies and clinical investigations to study new approaches and novel treatments.<\/jats:p>","DOI":"10.1136\/bcr-2025-265972","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T12:25:15Z","timestamp":1780662315000},"page":"e265972","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Hybrid adenoid cystic carcinoma of the palate with dual features"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9942-5647","authenticated-orcid":false,"given":"Preethi Narendra","family":"Sharma","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College and Hospital (Datta Meghe Institute of Higher Education and Research), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aayushi","family":"Pakhale","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Pathology and Microbiology, Shri Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankita","family":"Chavhan","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Pathology and Microbiology, Shri Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alka","family":"Hande","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Pathology and Microbiology, Shri Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, 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