{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:23:24Z","timestamp":1787318604811,"version":"build-2736575974"},"reference-count":11,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,8,13]]},"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:p>A paediatric patient was diagnosed with acute myeloid leukaemia (AML), with biallelic mutations in the transcription factor CCAAT\/enhancer binding protein \u03b1 (C\/EBP\u03b1). During her treatment, she developed recurrent episodes of febrile neutropenia with neutropenic colitis, leading to the development of an appendicovesical fistula (AVF) with drainage of feculent urine. She underwent laparotomy, division of the fistula with a wide margin of the bladder with repair, with appendicectomy which essentially cured the condition. This case report illustrated the unusual occurrence of AVF in a paediatric patient with AML and management essentially with an appendicectomy.<\/jats:p>","DOI":"10.1136\/bcr-2025-266420","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:50:14Z","timestamp":1787313014000},"page":"e266420","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Appendicovesical fistula in a child with acute myeloid leukaemia"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6408-0447","authenticated-orcid":false,"given":"Nitin","family":"Pai","sequence":"first","affiliation":[{"name":"Paediatric Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"},{"name":"Pediatric Surgical Oncology, Department of Surgical Oncology, Tata Memorial Hospital,Tata Memorial Centre, Mumbai, Maharastra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajid S","family":"Qureshi","sequence":"additional","affiliation":[{"name":"Pediatric Surgical Oncology, Department of Surgical Oncology, Tata Memorial Hospital,Tata Memorial Centre, Mumbai, Maharastra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1741-6634","authenticated-orcid":false,"given":"Geofia Shaina","family":"Crasta","sequence":"additional","affiliation":[{"name":"Paediatric Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"},{"name":"General Surgery, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Badira Cheriyalinkal","family":"Parambil","sequence":"additional","affiliation":[{"name":"Pediatric Hemato-Oncology, Tata Memorial Hospital, Tata Memorial Centre, Mumbai, Maharastra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2026082105201298000_19.8.e266420.1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3349\/ymj.2010.51.3.463","article-title":"Laparoscopic treatment of appendicovesical fistula","volume":"51","author":"Chung","year":"2010","journal-title":"Yonsei Med J"},{"key":"2026082105201298000_19.8.e266420.2","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2025.1610586","article-title":"Robot-assisted laparoscopic treatment of appendicovesical fistula in a child: a case report and literature review","volume":"13","author":"Fang","year":"2025","journal-title":"Front Pediatr"},{"key":"2026082105201298000_19.8.e266420.3","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1111\/ans.15805","article-title":"Fistulae involving the appendix: a systematic review of the literature","volume":"90","author":"McDonald","year":"2020","journal-title":"ANZ J Surg"},{"key":"2026082105201298000_19.8.e266420.4","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0090-4295(74)80127-5","article-title":"Ureteroappendiceal fistula in child","volume":"3","author":"Golimbu","year":"1974","journal-title":"Urology"},{"key":"2026082105201298000_19.8.e266420.5","first-page":"773","article-title":"Appendicovesical fistula","volume":"62","author":"Carson","year":"1979","journal-title":"Minn Med"},{"key":"2026082105201298000_19.8.e266420.6","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0022-5347(17)62234-1","article-title":"Appendico-vesical fistula","volume":"102","author":"Gross","year":"1969","journal-title":"J Urol"},{"key":"2026082105201298000_19.8.e266420.7","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004519404"},{"key":"2026082105201298000_19.8.e266420.8","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/0090-4295(84)90112-2","article-title":"Appendicovesical fistula","volume":"24","author":"Haas","year":"1984","journal-title":"Urology"},{"key":"2026082105201298000_19.8.e266420.9","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.1016\/j.urology.2024.04.023","article-title":"Diagnosis of Pediatric Appendicovesical Fistula by Contrast-enhanced Ultrasound: A Case Report","volume":"189","author":"Yang","year":"2024","journal-title":"Urology"},{"key":"2026082105201298000_19.8.e266420.10","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.231939","article-title":"Appendicovesical Fistula","volume":"309","author":"Wang","year":"2023","journal-title":"Radiology"},{"key":"2026082105201298000_19.8.e266420.11","doi-asserted-by":"crossref","unstructured":"Labib M , Mapulanga V . 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