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A round, dense mass measuring 5.60 cm\u00d75.17\u2009cm was identified in the right ventricle and right ventricular outflow tract, without involving the right atrium, causing obstruction of both the right ventricular inflow and outflow tracts. Subsequently, the patient underwent tricuspid valve (TV) replacement and surgical resection of the mass. The patient was ultimately diagnosed with undifferentiated small round cell sarcoma. One month after the surgery, the tumour recurred, and severe stenosis of the artificial TV suggested a poor prognosis for the sarcoma.<\/jats:p>","DOI":"10.1136\/bcr-2025-266549","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T03:45:13Z","timestamp":1764215113000},"page":"e266549","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primary undifferentiated small round cell sarcoma of the right ventricle with rapid recurrence and aggressive clinical presentation"],"prefix":"10.1136","volume":"18","author":[{"given":"Ye","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-lu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"2025112619450747000_18.11.e266549.1","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.radcr.2023.11.065","article-title":"Clinical presentation, diagnostic evaluation, and management of undifferentiated\/unclassified cardiac sarcoma: A case report and literature review","volume":"19","author":"Mohammadi","year":"2024","journal-title":"Radiol Case Rep"},{"key":"2025112619450747000_18.11.e266549.2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jaccao.2020.05.009","article-title":"Cardiac tumors: jacc cardiooncology state-of-the-art review","volume":"2","author":"Sara Tyebally","year":"2020","journal-title":"Jacc Cardiooncol"},{"key":"2025112619450747000_18.11.e266549.3","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2022-252198","article-title":"Primary undifferentiated high-grade pleomorphic cardiac sarcoma in the left atrium with atypical presentation","volume":"16","author":"Tan","year":"2023","journal-title":"BMJ Case Rep"},{"key":"2025112619450747000_18.11.e266549.4","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2024.1530403","article-title":"Case report: Primary cardiac undifferentiated sarcoma complicated by esophagus stenosis","volume":"14","author":"Ge","year":"2024","journal-title":"Front Oncol"},{"key":"2025112619450747000_18.11.e266549.5","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/1960593","article-title":"Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy with a High Propensity for Brain Metastases","volume":"2019","author":"Siontis","year":"2019","journal-title":"Sarcoma"},{"key":"2025112619450747000_18.11.e266549.6","doi-asserted-by":"crossref","DOI":"10.1007\/s12032-025-02661-0","article-title":"Diagnosis and treatment of cardiac tumors","volume":"42","author":"Imai","year":"2025","journal-title":"Med Oncol"},{"key":"2025112619450747000_18.11.e266549.7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/14737140.2020.1711738","article-title":"Current clinical management of primary cardiac sarcoma","volume":"20","author":"Siontis","year":"2020","journal-title":"Expert Rev Anticancer Ther"},{"key":"2025112619450747000_18.11.e266549.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2011.11.002"},{"key":"2025112619450747000_18.11.e266549.9","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr104"},{"key":"2025112619450747000_18.11.e266549.10","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0734-8"},{"key":"2025112619450747000_18.11.e266549.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.09.079"},{"key":"2025112619450747000_18.11.e266549.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.12.030"},{"key":"2025112619450747000_18.11.e266549.13","doi-asserted-by":"crossref","unstructured":"Mezri S , Zitouni C , Abid I , et al . 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