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This case report presents the anaesthetic approach to an infant with isolated non-syndromic sagittal craniosynostosis who successfully underwent cranial vault reconstruction in the sphinx position under general endotracheal anaesthesia maintained with sevoflurane and remifentanil. A thorough understanding of surgical and anaesthetic considerations perioperatively will guide the anaesthesiologist in planning individualised care for a positive patient outcome. Proper discussion with the neurosurgeon and surgical team about perioperative goals for the patient is a vital key to a successful procedure.<\/jats:p>","DOI":"10.1136\/bcr-2025-266735","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T04:35:14Z","timestamp":1757651714000},"page":"e266735","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Anaesthetic management of a patient with isolated non-syndromic sagittal craniosynostosis undergoing cranial vault reconstruction in the sphinx position"],"prefix":"10.1136","volume":"18","author":[{"given":"Joanna Domini","family":"Bernardino","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, University of the Philippines-Philippine General Hospital, Ermita, Metro Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geraldine Raphaela","family":"Jose","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University of the Philippines-Philippine General Hospital, Ermita, Metro Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"doi-asserted-by":"publisher","key":"2025091121350707000_18.9.e266735.1","DOI":"10.1016\/j.wneu.2022.05.093"},{"key":"2025091121350707000_18.9.e266735.2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/SCS.0000000000008188","article-title":"The Effect of Using In Vitro Fertilization (IVF) on Increasing the Prevalence of Craniosynostosis","volume":"33","author":"Kalantar-Hormozi","year":"2022","journal-title":"J craniofac surg"},{"doi-asserted-by":"publisher","key":"2025091121350707000_18.9.e266735.3","DOI":"10.1093\/bjaed\/mkw023"},{"key":"2025091121350707000_18.9.e266735.4","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1460-9592.2012.03927.x","article-title":"Anesthesia for surgery related to craniosynostosis: a review. 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