{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T05:05:53Z","timestamp":1768885553716,"version":"3.49.0"},"reference-count":19,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,1,6]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>The WHO categorises plasma cell tumours into two primary types: multiple myeloma and plasmacytoma. Plasmacytoma is further classified into solitary extramedullary plasmacytoma (EMP) and solitary plasmacytoma of bone. The upper respiratory tract and nasopharynx are the sites most commonly affected by EMP. Gastrointestinal tract involvement occurs in approximately 10% of EMP cases, while colonic involvement\u2014particularly when associated with intussusception\u2014is exceedingly rare. We present the case of a middle-aged man in his 40s who reported haematochezia, fatigue and weight loss over a 6-month period, without fever or bone pain. Physical examination revealed pallor. Endoscopic evaluation demonstrated a polypoidal mass at the hepatic flexure of the colon. An initial biopsy suggested a neuroendocrine tumour. Based on this provisional diagnosis, a D3 right extended hemicolectomy was performed. However, subsequent histopathological analysis unexpectedly revealed plasmacytoid cells consistent with EMP.<\/jats:p>","DOI":"10.1136\/bcr-2025-267404","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T16:20:17Z","timestamp":1768839617000},"page":"e267404","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Extramedullary plasmacytoma of the colon manifesting with intussusception"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8494-293X","authenticated-orcid":false,"given":"Ravi","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Gaurav","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahnawaz Ahmed","family":"Chowdhary","sequence":"additional","affiliation":[{"name":"Department of General Surgery, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"2026011908201281000_19.1.e267404.1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.2214\/ajr.183.4.1830929","article-title":"Spectrum of imaging findings in abdominal extraosseous myeloma","volume":"183","author":"Patlas","year":"2004","journal-title":"AJR Am J Roentgenol"},{"key":"2026011908201281000_19.1.e267404.2","unstructured":"Cotran RS , Kumar V , Robbins SL . Robbins and cotran pathologic basis of disease. 10th edn. 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Pancreatic Plasmacytoma Misdiagnosed as Neuroendocrine Tumour: A Pathologist\u2019s Dilemma. JCDR 2020. doi:10.7860\/JCDR\/2020\/43083.13534","DOI":"10.7860\/JCDR\/2020\/43083.13534"},{"key":"2026011908201281000_19.1.e267404.15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041875"},{"key":"2026011908201281000_19.1.e267404.16","doi-asserted-by":"crossref","DOI":"10.1111\/jne.13309","article-title":"European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for colorectal neuroendocrine tumours","volume":"35","author":"Rinke","year":"2023","journal-title":"J Neuroendocrinol"},{"key":"2026011908201281000_19.1.e267404.17","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.2147\/OTT.S372534","article-title":"A Durable Response of Primary Advanced Colonic Plasmacytoma Using a Combination of Surgical Resection and Adjuvant Bortezomib: A Case Report and Literature Review","volume":"15","author":"Alfar","year":"2022","journal-title":"Onco Targets Ther"},{"key":"2026011908201281000_19.1.e267404.18","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1182\/blood.V96.6.2037","article-title":"Solitary plasmacytoma of bone and asymptomatic multiple myeloma","volume":"96","author":"Dimopoulos","year":"2000","journal-title":"Blood"},{"key":"2026011908201281000_19.1.e267404.19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0219857","article-title":"Long-term clinical outcomes in a cohort of patients with solitary plasmacytoma treated in the modern era","volume":"14","author":"Sharpley","year":"2019","journal-title":"PLoS One"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-267404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T16:20:19Z","timestamp":1768839619000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-267404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,19]]},"published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1136\/bcr-2025-267404"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-267404","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]}}}