{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:05:51Z","timestamp":1756339551730,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,8,15]]},"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:p>Sickle cell disease may manifest as occlusion of arterial retinal vessels during a vaso-occlusive crisis, which can have multiple triggers. In this case, the patient had a simultaneous bilateral branch retinal artery occlusion, following physical activity, due to a sickle cell crisis. Timely treatment was started with exchange transfusion and erythrocytapheresis, which resulted in marked improvement of visual acuity and visual field over a 3-month follow-up. This case enlightens the importance of early recognition and communication with other medical specialties for prompt initiation of treatment and better functional results in a disease that is vision-threatening and normally associated with poor prognosis. In addition, this case emphasises the need for regular follow-up on patients with sickle cell disease to detect early signs of retinopathy and to alert patients to symptoms like episodes of transient loss of vision and the presence of scotomas.<\/jats:p>","DOI":"10.1136\/bcr-2025-267532","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:15:41Z","timestamp":1756314941000},"page":"e267532","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous bilateral branch retinal artery occlusion as a manifestation of sickle cell crisis: diagnostic and therapeutic implications"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1313-4847","authenticated-orcid":false,"given":"Madalena","family":"Sousa Gon\u00e7alves","sequence":"first","affiliation":[{"name":"Ophthalmology, Hospital Beatriz \u00c2ngelo, Loures, Lisbon, 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