{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T10:00:16Z","timestamp":1762941616372,"version":"3.45.0"},"reference-count":16,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,10,21]]},"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>Capgras syndrome, a delusional misidentification syndrome characterized by the belief that a close relative or friend has been replaced by an identical imposter, is a rare phenomenon often associated with psychotic disorders. Here, we present a case of a male in his early 80s with Lewy body dementia (LBD) who developed Capgras syndrome. Despite initial challenges in management, including thought blocking and word-finding difficulty, the patient experienced complete resolution of symptoms following treatment with rivastigmine, a cholinesterase inhibitor, commonly used in major neurocognitive disorders. This case highlights the potential efficacy of cholinesterase inhibitors in alleviating psychotic symptoms associated with Capgras syndrome, particularly in individuals with LBD.<\/jats:p>","DOI":"10.1136\/bcr-2025-267800","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:55:19Z","timestamp":1762941319000},"page":"e267800","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Successful resolution of Capgras syndrome with rivastigmine treatment in Lewy body dementia"],"prefix":"10.1136","volume":"18","author":[{"given":"Rameez","family":"Sultan","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachida","family":"Bouhenni","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Sasse","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silpa","family":"Balachandran","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"2025111201551058000_18.11.e267800.1","unstructured":"Shah KP , Jain SB , Wadhwa R . 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