{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:09Z","timestamp":1756374009340,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,7,28]]},"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:p>Primary pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of lung adenocarcinoma that resembles metastatic colorectal carcinoma in terms of morphology and immunophenotype. We describe a non-smoking female in her 30s who was referred for complaints of progressive low back pain, weight loss and fatigue. PET-CT revealed a 5.6 cm \u00d7 4.1 cm \u00d7 4.0\u2009cm left lower-lobe mass in the lung, metabolically active left\u2002supraclavicular lymphadenopathy, a segment IV lesion of the liver and extensive bony metastases.<\/jats:p>\n               <jats:p>A CT-guided biopsy revealed adenocarcinoma with mucin pools, and immunohistochemistry (IHC) showed diffuse positivity for CK7, CK20 and CDX2 and negativity for TTF-1, Napsin A and special AT-rich sequence-binding protein 2 (SATB2). These\u2002findings revealed the diagnosis of PEAC.<\/jats:p>\n               <jats:p>She underwent 6 cycles of cisplatin and pemetrexed chemotherapy\u2002with tolerable toxicity and a partial metabolic response on follow-up PET-CT. This case\u2002underscores the importance of a multimodal approach to differentiate PEAC from metastatic colorectal cancer and facilitate appropriate treatment.<\/jats:p>","DOI":"10.1136\/bcr-2025-267828","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T02:31:00Z","timestamp":1754965860000},"page":"e267828","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primary pulmonary enteric adenocarcinoma in a young adult: a diagnostic and therapeutic challenge"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0593-2141","authenticated-orcid":false,"given":"Karthikeyan","family":"Kaliyamurthi","sequence":"first","affiliation":[{"name":"Medical Oncology, Mahatma Gandhi Medical College and Research Institute, Puducherry, Pondicherry, India"},{"name":"Medical Oncology, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, Pondicherry, 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