{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:16:04Z","timestamp":1764317764543,"version":"3.46.0"},"reference-count":29,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,9,27]]},"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>Gallbladder paragangliomas are exceedingly rare neuroendocrine tumours, with fewer than 40 reported cases in the English literature. Paraganglioma of the cystic duct is even rarer, with only one prior case documented. We report the case of a male in his late 40s who presented with recurrent, intermittent abdominal pain and was diagnosed preoperatively with cholelithiasis. He underwent an elective laparoscopic cholecystectomy, after which postoperative histopathology revealed an incidental gallbladder paraganglioma with positive margins at the cystic duct. A metastatic work-up was negative, and the patient subsequently underwent laparoscopic re-excision of the cystic duct stump and regional lymphadenectomy. Histology confirmed residual tumour with negative margins and no nodal metastasis. The patient remains under short-term follow-up. This case underscores the diagnostic and therapeutic challenges of incidental gallbladder paraganglioma, particularly when surgical margins are involved, and highlights the need for individualised management in the absence of formal guidelines.<\/jats:p>","DOI":"10.1136\/bcr-2025-268038","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T11:15:21Z","timestamp":1760699721000},"page":"e268038","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Gallbladder and cystic duct paraganglioma requiring cystic duct re-excision"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0565-471X","authenticated-orcid":false,"given":"Rahma","family":"Abdelaziz","sequence":"first","affiliation":[{"name":"General Surgery, NMC Healthcare Ltd, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6190-8834","authenticated-orcid":false,"given":"Gilbert","family":"Ayoub","sequence":"additional","affiliation":[{"name":"General Surgery, NMC Healthcare Ltd, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2472-5973","authenticated-orcid":false,"given":"Hassan","family":"Elberm","sequence":"additional","affiliation":[{"name":"General Surgery, NMC Healthcare Ltd, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2700-0469","authenticated-orcid":false,"given":"Raghda","family":"Tarek","sequence":"additional","affiliation":[{"name":"Medical Oncology, Mansoura University Oncology Centre, Mansoura, Dakahlia Governorate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juman","family":"Abu Hazeem","sequence":"additional","affiliation":[{"name":"General Surgery, NMC Healthcare Ltd, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,10,17]]},"reference":[{"key":"2025112800150768000_18.10.e268038.1","article-title":"Gallbladder Paraganglioma: A Mysterious Histological Finding","volume":"15","author":"Do","year":"2023","journal-title":"Cureus"},{"key":"2025112800150768000_18.10.e268038.2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/rg.231025050","article-title":"Neurogenic tumors in the abdomen: tumor types and imaging characteristics","volume":"23","author":"Rha","year":"2003","journal-title":"Radiographics"},{"key":"2025112800150768000_18.10.e268038.3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ijscr.2018.09.041","article-title":"A rare case of paraganglioma of the cystic duct","volume":"52","author":"AlMarzooqi","year":"2018","journal-title":"Int J Surg Case Rep"},{"key":"2025112800150768000_18.10.e268038.4","unstructured":"Pacak K , Tella SH . 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