{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:19:17Z","timestamp":1788437957105,"version":"build-2803163510"},"reference-count":15,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,4,30]]},"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>Solitary extramedullary plasmacytoma (SEP) is a rare plasma cell tumour that occurs in soft tissues without systemic involvement. This report describes a rare case of SEP in the nasal cavity, highlighting the diagnostic journey and treatment approach. The patient\u2019s nonspecific symptoms, such as right-sided nasal bleeding and facial pain, initially mimicked common nasal disorders. However, the persistence of these symptoms and the discovery of a polypoid mass on nasal endoscopy raised suspicions of a more serious underlying condition, leading to further investigation. Histopathological analysis confirmed SEP after excluding systemic myeloma. Investigations revealed normal renal function, calcium levels, blood counts and no lytic lesions on imaging. Serum and urine electrophoresis were negative for monoclonal proteins, and bone marrow examination revealed less than 10% plasma cells. The patient received curative radiotherapy. Early follow-up showed clinical stability and a structured multidisciplinary follow-up plan was instituted to monitor disease recurrence or progression to multiple myeloma.<\/jats:p>","DOI":"10.1136\/bcr-2025-268154","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T12:30:17Z","timestamp":1779971417000},"page":"e268154","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Solitary extramedullary plasmacytoma of the nasal cavity: integrating clinical, radiological and histological findings"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0593-2141","authenticated-orcid":false,"given":"Karthikeyan","family":"Kaliyamurthi","sequence":"first","affiliation":[{"name":"Medical Oncology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishva","family":"Babu","sequence":"additional","affiliation":[{"name":"Medical Oncology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amarnath","family":"Gopalraj","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Krishna Cancer Institute, Cuddalore, Tamilnadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavani","family":"Krishnamurthy","sequence":"additional","affiliation":[{"name":"Pathology, Mahatma Gandhi Medical College and Research Institute, Sri balaji Vidyapeeth university, Puducherry, PY, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"2026090305052472000_19.5.e268154.1","article-title":"Solitary extramedullaryplasmacytoma: 10-year experience of a single institution","volume":"22","author":"Shih","year":"2022","journal-title":"BMC Cancer"},{"key":"2026090305052472000_19.5.e268154.2","doi-asserted-by":"crossref","first-page":"4060","DOI":"10.1007\/s12070-023-04061-0","article-title":"Solitary Extramedullary Plasmacytoma of Nasal Cavity","volume":"75","author":"Mishra","year":"2023","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"2026090305052472000_19.5.e268154.3","unstructured":"Lee JH , Lim Y , Kim SW , et al . 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