{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T12:29:52Z","timestamp":1767356992774,"version":"3.48.0"},"reference-count":16,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"unspecified","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Emporia s r.o., Krompachy, Slovakia"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,11,22]]},"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>This study describes a case of an umbilical cord haemangioma diagnosed during a first-trimester ultrasound examination in the 13th week of gestation. The anomaly initially presented as a double cystic lesion located in the mid-portion of the umbilical cord. Subsequent ultrasound scans revealed a hyperechoic solid structure within the cystic lesion near the umbilical vessels, and an umbilical cord haemangioma was suspected. Given the possible fetal complications related to the growth of the lesion, serial ultrasound examinations with detailed Doppler flow studies of the lesion were performed. The pregnancy progressed without complications, and the patient underwent elective caesarean delivery at term. The histopathological examination of the cord confirmed a benign capillary haemangioma with pseudocystic degeneration of Wharton\u2019s jelly. Postnatally, a small cutaneous haemangioma was noted on the scalp of the newborn.<\/jats:p>","DOI":"10.1136\/bcr-2025-268227","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T09:45:17Z","timestamp":1764927917000},"page":"e268227","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Umbilical cord haemangioma with pseudocyst detected in the first trimester of pregnancy"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7195-1407","authenticated-orcid":false,"given":"Svetlana","family":"J\u00e1no\u0161ov\u00e1","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pavol Jozef Stafarik University in Kosice Faculty of Medicine, Ko\u0161ice, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rastislav","family":"Dudi\u010d","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pavol Jozef Stafarik University in Kosice Faculty of Medicine, Ko\u0161ice, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00f3bert","family":"Dankov\u010d\u00edk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pavol Jozef Stafarik University in Kosice Faculty of Medicine, Ko\u0161ice, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"P\u0161enkov\u00e1","sequence":"additional","affiliation":[{"name":"2nd Department of Gynecology and Obstetrics, University Hospital Bratislava, Bratislava, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"2026010204250784000_18.12.e268227.1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1177\/10935266241264161","article-title":"Umbilical Cord Hemangiomas: A Multi-Institutional Case Series With Literature Review","volume":"27","author":"Ferreira","year":"2024","journal-title":"Pediatr Dev Pathol"},{"key":"2026010204250784000_18.12.e268227.2","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1002\/jum.16506","article-title":"Prenatal Diagnosis of Umbilical Cord Angiomyxoma: Case Studies and Literature Review of 45 Cases","volume":"43","author":"Grossi","year":"2024","journal-title":"Ultrasound Med"},{"key":"2026010204250784000_18.12.e268227.3","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0022-3468(97)90625-4","article-title":"Hemangioma of the umbilical cord mimicking an omphalocele","volume":"32","author":"Miller","year":"1997","journal-title":"J Pediatr Surg"},{"key":"2026010204250784000_18.12.e268227.4","doi-asserted-by":"crossref","first-page":"13","DOI":"10.32074\/1591-951X-26-17","article-title":"Hemangioma of the umbilical cord with associated amnionic inclusion cyst: two uncommon entities occurring simultaneously","volume":"111","author":"Angelico","year":"2019","journal-title":"Pathologica"},{"key":"2026010204250784000_18.12.e268227.5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3109\/15513811003796920","article-title":"Hemangioma of the umbilical cord with pseudocyst","volume":"30","author":"Matsuda","year":"2011","journal-title":"Fetal Pediatr Pathol"},{"key":"2026010204250784000_18.12.e268227.6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/uog.24755","article-title":"Prenatal diagnosis of umbilical cord hemangioma","volume":"59","author":"Lok","year":"2022","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2026010204250784000_18.12.e268227.7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejogrb.2009.01.011","article-title":"A case of umbilical cord hemangioma: Doppler studies and review of the literature","volume":"144","author":"Papadopoulos","year":"2009","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2026010204250784000_18.12.e268227.8","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/pd.1109","article-title":"The association of umbilical cord hemangioma with fetal vascular birthmarks","volume":"25","author":"Daniel-Spiegel","year":"2005","journal-title":"Prenat Diagn"},{"key":"2026010204250784000_18.12.e268227.9","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcu.22346","article-title":"The natural history of an umbilical cord hemangioma","volume":"44","author":"Smulian","year":"2016","journal-title":"J Clin Ultrasound"},{"key":"2026010204250784000_18.12.e268227.10","doi-asserted-by":"crossref","first-page":"156","DOI":"10.5858\/arpa.2019-0161-RA","article-title":"Umbilical Cord Teratomas Associated With Congenital Malformations","volume":"144","author":"Adams","year":"2020","journal-title":"Arch Pathol Lab Med"},{"key":"2026010204250784000_18.12.e268227.11","unstructured":"Sepulveda W . Umbilical cord abnormalities: prenatal diagnosis and management. UpToDate. Available: https:\/\/www.uptodate.com\/contents\/umbilical-cord-abnormalieties-prenatal-diagnosis-and-management [Accessed Oct 2023]."},{"key":"2026010204250784000_18.12.e268227.12","unstructured":"Heerema-McKenney A , Popek EJ , De Paepe ME . Histopathologic changes of umbilical cord. In: Diagnostic pathology: placenta, 3rd ed. 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