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Our case illustrates a rare presentation of SCLC with an intention to highlight the importance of evaluating for malignancy and associated paraneoplastic syndromes in patients with unexplained encephalopathy.<\/jats:p>","DOI":"10.1136\/bcr-2025-268896","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T16:20:20Z","timestamp":1770049220000},"page":"e268896","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Anti-AMPAR limbic encephalitis as the initial presentation of metastatic small cell cancer"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0223-3118","authenticated-orcid":false,"given":"Chandra L","family":"Kakarala","sequence":"first","affiliation":[{"name":"Internal Medicine, University of Kentucky, Lexington, Kentucky, 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