{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:53:16Z","timestamp":1767678796499,"version":"3.48.0"},"reference-count":14,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,12,5]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>A middle childhood boy with homozygous sickle cell disease (SCD) on hydroxyurea, previously healthy, presented with acute bilateral limb pain progressing rapidly to altered sensorium and signs of raised intracranial pressure. Cranial CT revealed bilateral epidural haematomas with a large left fronto-parietal epidural haematoma (EDH) and midline shift. He underwent urgent craniotomy, mechanical ventilation, blood transfusion and phenobarbitone coma for autonomic instability. He recovered with initial right hemiparesis that improved to independent ambulation without limitation, with no recurrence on follow-up. This case represents the youngest documented survivor of spontaneous EDH in SCD, emphasising that non-traumatic intracranial bleeding can occur even at early ages in SCD patients. Emergency physicians should remain alert to this rare possibility in young children with SCD.<\/jats:p>","DOI":"10.1136\/bcr-2025-269512","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:50:11Z","timestamp":1767678611000},"page":"e269512","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Breaking age barriers: spontaneous epidural haematoma in a child with sickle cell disease"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9214-4880","authenticated-orcid":false,"given":"Bipin Bihari","family":"Rout","sequence":"first","affiliation":[{"name":"Paediatrics, All India Institute of Medical Sciences Raipur, Raipur, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santosh","family":"Navi","sequence":"additional","affiliation":[{"name":"Paediatrics, All India Institute of Medical Sciences Raipur, Raipur, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raju","family":"S M","sequence":"additional","affiliation":[{"name":"Paediatrics, All India Institute of Medical Sciences Raipur, Raipur, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil Kumar","family":"Goel","sequence":"additional","affiliation":[{"name":"Paediatrics, All India Institute of Medical Sciences Raipur, Raipur, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"2026010521500878000_19.1.e269512.1","doi-asserted-by":"crossref","first-page":"e558","DOI":"10.1016\/S2352-3026(23)00169-2","article-title":"Sickle cell disease: time to act on the most neglected global health problem","volume":"10","author":"Osei","year":"2023","journal-title":"Lancet Haematol"},{"key":"2026010521500878000_19.1.e269512.2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-1241"},{"key":"2026010521500878000_19.1.e269512.3","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s00381-023-06235-1","article-title":"Non-traumatic bilateral epidural hematoma in a child with sickle cell anemia: A case report and a review of the literature","volume":"40","author":"Aljohani","year":"2024","journal-title":"Childs Nerv Syst"},{"key":"2026010521500878000_19.1.e269512.4","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411414441"},{"key":"2026010521500878000_19.1.e269512.5","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3171\/2009.7.PEDS09219","article-title":"A \u201cneurosurgical crisis\u201d of sickle cell disease","volume":"4","author":"Dahdaleh","year":"2009","journal-title":"PED"},{"key":"2026010521500878000_19.1.e269512.6","first-page":"38","article-title":"Management of Spontaneous Epidural Hematoma in the Setting of Vaso-occlusive Crisis Among Pediatric Patients With Sickle Cell Disease: A Case Series and Scoping Literature Review","volume":"47","author":"Patel","year":"2025","journal-title":"J Pediatr Hematol Oncol"},{"key":"2026010521500878000_19.1.e269512.7","doi-asserted-by":"crossref","first-page":"176","DOI":"10.59628\/jchm.v19i2.1639","article-title":"Assessment of D-dimer level among Yemeni Patients with Sickle Cell Anemia","volume":"19","author":"Haj","year":"2025","journal-title":"Jchm"},{"key":"2026010521500878000_19.1.e269512.8","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-224504","article-title":"Acute spontaneous intracranial epidural haematoma and disseminated intravascular coagulation in a paediatric sickle cell patient","volume":"2018","author":"Banerjee","year":"2018","journal-title":"BMJ Case Rep"},{"key":"2026010521500878000_19.1.e269512.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2012.08.307"},{"key":"2026010521500878000_19.1.e269512.10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00381-022-05721-2","article-title":"Erythrapheresis and medical treatment in pediatric sickle cell disease cranial epidural hematomas: 2 cases","volume":"39","author":"Tann\u00e9","year":"2023","journal-title":"Childs Nerv Syst"},{"key":"2026010521500878000_19.1.e269512.11","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/ajh.23579","article-title":"Nontraumatic extradural hematoma in sickle cell anemia: A rare neurological complication not to be missed","volume":"89","author":"Page","year":"2014","journal-title":"American J Hematol"},{"key":"2026010521500878000_19.1.e269512.12","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1007\/s00701-015-2582-6","article-title":"A review of spontaneous intracranial extradural hematoma in sickle-cell disease","volume":"157","author":"Hettige","year":"2015","journal-title":"Acta Neurochir (Wien)"},{"key":"2026010521500878000_19.1.e269512.13","article-title":"Spontaneous Epidural Hemorrhage in Sickle Cell Disease, Are They All the Same? 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