{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T13:38:10Z","timestamp":1771508290067,"version":"3.50.1"},"reference-count":14,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,1,28]]},"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>We report the case of a successful caesarean delivery in a woman with von Willebrand disease (VWD) which poses significant risk of maternal bleeding during childbirth. The patient, a primigravida with known type 2 VWD, was closely monitored throughout gestation with periodic assessment of coagulation profile, von Willebrand factor activity and factor VIII levels. A multidisciplinary team\u2014including obstetricians, haematologists, transfusion medicine specialists and anaesthesiologists\u2014was involved and delivery was planned at 39 weeks\u2019 gestation with preparedness for factor replacement. Prophylactic tranexamic acid was administered at induction of labour. Patient landed up in a caesarean section because of pathological cardiotocography with meconium staining. Prophylactic factor VIII replacement therapy was given at induction of anaesthesia to minimise haemorrhagic risk. A caesarean section was performed uneventfully, with no intraoperative or postoperative bleeding complications. Both mother and neonate had a favourable outcome.<\/jats:p>","DOI":"10.1136\/bcr-2025-269612","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:55:19Z","timestamp":1771505719000},"page":"e269612","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Peripartum management of caesarean delivery in type 2 von Willebrand disease"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2997-8726","authenticated-orcid":false,"given":"Sumanjot","family":"Kaur","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanjot","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riya","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Sikka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seema","family":"Chopra","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"2026021904550893000_19.2.e269612.1","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1182\/blood.V69.2.454.454","article-title":"Epidemiological investigation of the prevalence of von Willebrand\u2019s disease","volume":"69","author":"Rodeghiero","year":"1987","journal-title":"Blood"},{"key":"2026021904550893000_19.2.e269612.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80384-1"},{"key":"2026021904550893000_19.2.e269612.3","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1111\/hae.14804","article-title":"Von Willebrand Disease: Gaining a global perspective","volume":"29","author":"O\u2019Sullivan","year":"2023","journal-title":"Haemophilia"},{"key":"2026021904550893000_19.2.e269612.4","doi-asserted-by":"crossref","DOI":"10.1186\/s12959-025-00727-7","article-title":"Von Willebrand disease (VWD) and pregnancy: a comprehensive overview","volume":"23","author":"Soleimani Samarkhazan","year":"2025","journal-title":"Thromb J"},{"key":"2026021904550893000_19.2.e269612.5","doi-asserted-by":"crossref","DOI":"10.11604\/pamj.2017.27.147.12248","article-title":"Von Willebrand\u2019s disease: case report and review of literature","volume":"27","author":"Echahdi","year":"2017","journal-title":"Pan Afr Med J"},{"key":"2026021904550893000_19.2.e269612.6","doi-asserted-by":"crossref","first-page":"4602","DOI":"10.18203\/2320-1770.ijrcog20214673","article-title":"Von Willebrand disease in pregnancy: a case report","volume":"10","author":"G","year":"2021","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"2026021904550893000_19.2.e269612.7","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(82)90729-X"},{"key":"2026021904550893000_19.2.e269612.8","first-page":"e193","article-title":"Management of Inherited Bleeding Disorders in Pregnancy","volume":"124","year":"2017","journal-title":"BJOG"},{"key":"2026021904550893000_19.2.e269612.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01150.x"},{"key":"2026021904550893000_19.2.e269612.10","doi-asserted-by":"crossref","unstructured":"Mu\u00f1oz Vargas BA , Contreras Valero SJ , Aragon Mendoza RL , et al . Von Willebrand Disease and Pregnancy: Management Protocol From Labor to the Postpartum Period. 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Caesarean birth. London: NICE, 2021."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-269612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:55:21Z","timestamp":1771505721000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-269612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":14,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,2,19]]},"published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1136\/bcr-2025-269612"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-269612","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]}}}