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Patients were treated with multiday intravenous ketamine infusions (target dose 30 mg\/hour) every 3\u20136 months, supplemented with oral ketamine troches. This treatment protocol resulted in the complete resolution of dystonia in two patients and significant functional improvement in the third. The treatment was well-tolerated, with transient and manageable adverse events including nausea and hypertension. While these findings are limited due to the small sample size and lack of randomisation, this case report presents a potentially promising therapeutic approach for the treatment of CRPS-related motor complications in carefully selected patients with appropriate monitoring.<\/jats:p>","DOI":"10.1136\/bcr-2025-269687","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T15:30:27Z","timestamp":1773934227000},"page":"e269687","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Long-term relief of CRPS-associated limb dystonia with ketamine infusion"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8719-6299","authenticated-orcid":false,"given":"Abdulrahman","family":"AlZahrani","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Neurology, The University of British Columbia Faculty of Medicine, Vancouver, British Columbia, 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