{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T02:07:38Z","timestamp":1768442858226,"version":"3.49.0"},"reference-count":26,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,12,30]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:italic>Cryptococcus neoformans<\/jats:italic>\n                    most commonly causes pulmonary and central nervous system infections, with skeletal involvement usually occurring as part of disseminated disease in profoundly immunocompromised hosts. We describe an HIV-negative man in his early 50s from South Africa with sarcoidosis, type 1 diabetes mellitus and chronic kidney disease who presented with a 1\u2009month history of a localised swelling over the right anterior chest wall. CT demonstrated an expansile lesion of the right sixth anterior rib. Biopsy and culture confirmed\n                    <jats:italic>C. neoformans<\/jats:italic>\n                    with fluconazole non-susceptibility. The patient was treated with 12 months of voriconazole, achieving clinical and radiological resolution without surgical intervention.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2025-269841","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T15:30:20Z","timestamp":1768404620000},"page":"e269841","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Cryptococcus neoformans<\/i>\n                    causing localised osteomyelitis of the right anterior rib"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7814-1167","authenticated-orcid":false,"given":"Stephen P","family":"Connolly","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Cork University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Shannon","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Cork University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"O\u2019Mahony","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Cork University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Cork University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"2026011407301113000_19.1.e269841.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2015.10.006"},{"key":"2026011407301113000_19.1.e269841.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2311057"},{"key":"2026011407301113000_19.1.e269841.3","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01115-12"},{"key":"2026011407301113000_19.1.e269841.4","doi-asserted-by":"publisher","DOI":"10.1086\/649858"},{"key":"2026011407301113000_19.1.e269841.5","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e37514","article-title":"Cryptococcus neoformans osteomyelitis of the radius treatment with antifungal calcium sulphate: A case report and literature review","volume":"10","author":"Li","year":"2024","journal-title":"Heliyon"},{"key":"2026011407301113000_19.1.e269841.6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0072222","article-title":"Geographically structured populations of Cryptococcus neoformans var. grubii correlate with HIV status","volume":"8","author":"Khayhan","year":"2013","journal-title":"PLoS One"},{"key":"2026011407301113000_19.1.e269841.7","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1093\/cid\/ciad321","article-title":"Epidemiology and clinical features of cryptococcal infection in HIV-negative patients","volume":"77","author":"Coussement","year":"2023","journal-title":"Clin Infect Dis"},{"key":"2026011407301113000_19.1.e269841.8","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(22)00499-6"},{"key":"2026011407301113000_19.1.e269841.9","doi-asserted-by":"crossref","DOI":"10.1093\/mmy\/myae043","article-title":"Cryptococcosis-a systematic review to inform the World Health Organization Fungal Priority Pathogens List","volume":"62","author":"Dao","year":"2024","journal-title":"Med Mycol"},{"key":"2026011407301113000_19.1.e269841.10","unstructured":"MSG07 Study Group . International cohort study comparing epidemiology and outcomes of Cryptococcus neoformans and C. gattii infections. Clin Infect Dis 2021. 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