{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:07:00Z","timestamp":1772118420853,"version":"3.50.1"},"reference-count":24,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,2,9]]},"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    Phosphaturic mesenchymal tumours (PMTs) are rare benign tumours that secrete fibroblast growth factor 23 (FGF23), leading to phosphate wasting, disordered vitamin D metabolism and impaired bone mineralisation, clinically known as tumour-induced osteomalacia. PMTs are frequently misdiagnosed due to rarity and non-specific presentation. We report a case of a male in his 60s who presented to the hospital with 7 years of progressive muscle weakness and diffuse pain, resulting in inability to walk. His work-up was significant for hypophosphataemia with imaging showing chronic bilateral femoral neck fractures and 11 posterior rib fractures. Copper-64 DOTA-Phe\n                    <jats:sup>1<\/jats:sup>\n                    -Tyr\n                    <jats:sup>3<\/jats:sup>\n                    -Thr\n                    <jats:sup>8<\/jats:sup>\n                    -octreotate positron emission tomography\/CT demonstrated increased uptake within the left femur. Venous sampling revealed elevated FGF23. He underwent resection of the femoral tumour with histology consistent with PMT. Within 1 year of resection, the patient showed significant improvement. This case highlights the diagnostic challenge of PMTs and the dramatic improvement that can occur following resection.\u2003\n                  <\/jats:p>","DOI":"10.1136\/bcr-2025-270100","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:00:13Z","timestamp":1772114413000},"page":"e270100","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral femoral neck fractures and 11 rib fractures unmask tumour-induced osteomalacia caused by a phosphaturic mesenchymal tumour"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3531-033X","authenticated-orcid":false,"given":"Sydney","family":"Corey","sequence":"first","affiliation":[{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7912-3104","authenticated-orcid":false,"given":"Sanjana","family":"Sathrasala","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SM","family":"Burnett-Bowie","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Endocrine Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura R","family":"Glick","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"2026022606000493000_19.2.e270100.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020881"},{"key":"2026022606000493000_19.2.e270100.2","doi-asserted-by":"crossref","DOI":"10.1016\/j.bonr.2024.101772","article-title":"Tumor-induced osteomalacia: A systematic literature review","volume":"21","author":"\u00c1lvarez-Rivas","year":"2024","journal-title":"Bone Rep"},{"key":"2026022606000493000_19.2.e270100.3","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200401000-00001"},{"key":"2026022606000493000_19.2.e270100.4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870415)59:8<1442::AID-CNCR2820590810>3.0.CO;2-Q"},{"key":"2026022606000493000_19.2.e270100.5","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1881"},{"key":"2026022606000493000_19.2.e270100.6","doi-asserted-by":"crossref","unstructured":"Brandi ML , Clunie GPR , Houillier P , et al . 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