{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:53:22Z","timestamp":1767678802198,"version":"3.48.0"},"reference-count":6,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2025,12,14]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Primary cutaneous aspergillosis is a rare fungal infection in extremely preterm neonates. We report a male infant born at 25+5 weeks\u2019 gestation who developed necrotic lesions at the site of an umbilical catheter covered with an occlusive dressing. Culture confirmed\n                    <jats:italic>Aspergillus fumigatus<\/jats:italic>\n                    , and systemic liposomal amphotericin B combined with local enzymatic debridement and a non-adherent silicone wound contact layer was initiated after receipt of the culture result. The lesions resolved completely, leaving only a fine residual scar without functional impairment.\n                  <\/jats:p>\n                  <jats:p>This case emphasises the importance of early recognition, culture-based diagnosis and timely antifungal therapy in preterm neonates with catheter-related skin lesions, even when standard antifungal prophylaxis has been administered.<\/jats:p>","DOI":"10.1136\/bcr-2025-270565","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:50:21Z","timestamp":1767678621000},"page":"e270565","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Early recognition and management of primary cutaneous aspergillosis in an extremely preterm neonate associated with an umbilical catheter"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6816-2414","authenticated-orcid":false,"given":"Mar\u00eda del Pilar","family":"Mart\u00edn-Tamayo Bl\u00e1zquez","sequence":"first","affiliation":[{"name":"Pediatric, Hospital Universitario de Jerez de la Frontera, Jerez de la Frontera, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Teresa","family":"De Benito Guerra","sequence":"additional","affiliation":[{"name":"Pediatric, Hospital Universitario de Jerez de la Frontera, Jerez de la Frontera, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Ruiz Oca\u00f1a","sequence":"additional","affiliation":[{"name":"Pediatric, Hospital Universitario de Jerez de la Frontera, Jerez de la Frontera, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"G\u00f3mez-Pastrana Dur\u00e1n","sequence":"additional","affiliation":[{"name":"Pediatric, Hospital Universitario de Jerez de la Frontera, Jerez de la Frontera, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"2026010521501733000_19.1.e270565.1","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2014-204752","article-title":"Primary cutaneous aspergillosis in a preterm neonate","volume":"2014","author":"Rogdo","year":"2014","journal-title":"BMJ Case Rep"},{"key":"2026010521501733000_19.1.e270565.2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2002.00203.x"},{"key":"2026010521501733000_19.1.e270565.3","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1186\/s12879-017-2646-8","article-title":"Simultaneous primary invasive cutaneous aspergillosis in two preterm twins: case report and review of the literature","volume":"17","author":"Gallais","year":"2017","journal-title":"BMC Infect Dis"},{"key":"2026010521501733000_19.1.e270565.4","first-page":"13","article-title":"Primary cutaneous aspergillosis in premature neonates: case series and literature review","volume":"36","author":"Wada","year":"2022","journal-title":"Med Mycol Case Rep"},{"key":"2026010521501733000_19.1.e270565.5","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.6.1102"},{"key":"2026010521501733000_19.1.e270565.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2011.06.012"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-270565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:50:22Z","timestamp":1767678622000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-270565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,5]]},"published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1136\/bcr-2025-270565"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-270565","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2026,1]]}}}