{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:17:05Z","timestamp":1790615825641,"version":"4.1.0"},"reference-count":16,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,8,27]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>Glomus tumours (GTs) are rare mesenchymal neoplasms originating from modified myoid cells of the glomus body which is involved in thermoregulation and skin circulation. Primary renal involvement is exceedingly rare and has been reported only sporadically in the medical literature. Although typically benign, these tumours can occasionally exhibit aggressive or malignant behaviour. This article presents two cases of renal GT with uncertain malignant potential. Both patients, elderly individuals presenting with abdominal pain, were found to have large parenchymal renal masses on radiological evaluation. They underwent nephrectomy, followed by detailed histopathological and immunohistochemical analysis. While the tumours displayed atypical features, they did not meet the established criteria for malignancy. Postoperative follow-up revealed a benign clinical course, with no signs of local recurrence or metastasis.<\/jats:p>","DOI":"10.1136\/bcr-2025-271360","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:31:55Z","timestamp":1790613115000},"page":"e271360","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primary renal glomus tumours of uncertain malignant potential: diagnostic challenges and insights from two instances"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8873-7844","authenticated-orcid":false,"given":"Bhavika","family":"Sharma","sequence":"first","affiliation":[{"name":"Pathology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chippy Elizabeth","family":"Jose","sequence":"additional","affiliation":[{"name":"Pathology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyotsna","family":"Yesodharan","sequence":"additional","affiliation":[{"name":"Pathology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bindhu","family":"Mangalath Rajamma","sequence":"additional","affiliation":[{"name":"Pathology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"2026092809300890000_19.9.e271360.1","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.5858\/2008-132-1448-GT","article-title":"Glomus Tumor","volume":"132","author":"Gombos","year":"2008","journal-title":"Arch Pathol Lab Med"},{"key":"2026092809300890000_19.9.e271360.2","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.5858\/2005-129-1172-GGTOTK","article-title":"Glomangiomyoma (glomus tumor) of the kidney","volume":"129","author":"Siddiqui","year":"2005","journal-title":"Arch Pathol Lab Med"},{"key":"2026092809300890000_19.9.e271360.3","first-page":"1517","article-title":"Glomus Tumor in Kidney: A Case Report and Review of Literature","volume":"7","author":"Hsieh","year":"2023","journal-title":"Clin Case Rep Int"},{"key":"2026092809300890000_19.9.e271360.4","first-page":"459","article-title":"Primary renal glomus tumor with concurrent papillary renal cell carcinoma and multiple papillary adenomas in a patient with end stage renal disease: a case report and clinicopathologic analysis","volume":"15","author":"Bhardwaj","year":"2022","journal-title":"Int J Clin Exp Pathol"},{"key":"2026092809300890000_19.9.e271360.5","doi-asserted-by":"publisher","DOI":"10.1177\/1066896908331233"},{"key":"2026092809300890000_19.9.e271360.6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.15586\/jkcvhl.v11i1.298","article-title":"Inoperable Renal Malignant Glomus Tumor, the answers for all the \u201cW\u2019s\u201d?","volume":"11","author":"Surianarayanan","year":"2024","journal-title":"J Kidney Cancer VHL"},{"key":"2026092809300890000_19.9.e271360.7","unstructured":"Hoda SA . Enzinger and Weiss\u2019s soft tissue tumors. 6th edn. Philadelphia: Wolters Kluwer, 2020."},{"key":"2026092809300890000_19.9.e271360.8","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213373.64053.41"},{"key":"2026092809300890000_19.9.e271360.9","doi-asserted-by":"crossref","first-page":"126","DOI":"10.2478\/amma-2018-0018","article-title":"Glomus Tumor of the Kidney: Case report","volume":"64","author":"Dee","year":"2018","journal-title":"Acta Medica Marisiensis"},{"key":"2026092809300890000_19.9.e271360.10","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199602000-00012"},{"key":"2026092809300890000_19.9.e271360.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2004.10.005"},{"key":"2026092809300890000_19.9.e271360.12","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200101000-00001"},{"key":"2026092809300890000_19.9.e271360.13","doi-asserted-by":"crossref","first-page":"e253","DOI":"10.1016\/j.clgc.2017.09.002","article-title":"Characterization of Glomus Tumors of the Kidney","volume":"16","author":"Li","year":"2018","journal-title":"Clin Genitourin Cancer"},{"key":"2026092809300890000_19.9.e271360.14","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.humpath.2010.11.009","article-title":"Malignant glomus tumor of kidney: the first reported case and review of literature","volume":"42","author":"Lamba","year":"2011","journal-title":"Hum Pathol"},{"key":"2026092809300890000_19.9.e271360.15","first-page":"100102","article-title":"Primary glomus tumor of the kidney","volume":"4","author":"Aarthiprabha","year":"2021","journal-title":"Curr Probl Cancer Case Rep"},{"key":"2026092809300890000_19.9.e271360.16","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.humpath.2017.04.005","article-title":"Pericytic tumors of the kidney-a clinicopathologic analysis of 17 cases","volume":"64","author":"Sirohi","year":"2017","journal-title":"Hum Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-271360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:31:59Z","timestamp":1790613119000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-271360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":16,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9,28]]},"published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1136\/bcr-2025-271360"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-271360","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]}}}