{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:08:24Z","timestamp":1790240904014,"version":"4.1.0"},"reference-count":14,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,8,27]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>Synovial sarcoma (SS) represents a rare malignant type of soft tissue sarcoma (STS) with uncertain differentiation accounting for 5%\u201310%\u2009of all STS. Primary renal synovial sarcoma (PRSS) is very rare, with only about 205 documented cases so far with predominantly monophasic morphology. Clinical and radiological presentations of PRSS as renal mass, abdominal pain and haematuria often make it difficult to distinguish from other renal malignancies like renal cell carcinoma (RCC). The occurrence of both carcinoma and sarcoma simultaneously in the same kidney is rare. Due to the rarity and severity of the disease, diagnosis and management rely on a multidisciplinary approach. Here we reported a diagnostically challenging case of a patient in his 50s with primary biphasic SS of the kidney with synchronous clear cell RCC. To the best of our knowledge, this is the first documented case of a patient developing PRSS with synchronous clear cell RCC.<\/jats:p>","DOI":"10.1136\/bcr-2025-271512","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:40:11Z","timestamp":1790239211000},"page":"e271512","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Renal synovial sarcoma occurring synchronously with renal cell carcinoma"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5066-3458","authenticated-orcid":false,"given":"Deevanshi","family":"Manchanda","sequence":"first","affiliation":[{"name":"Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Krishna","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakshatha","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hema","family":"Kini","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"2026092401400761000_19.9.e271512.1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol28030177"},{"key":"2026092401400761000_19.9.e271512.2","doi-asserted-by":"crossref","unstructured":"Mhaske S , Singh S , Satav VP , et al . Management of Metastatic Primary Renal Synovial Sarcoma with Inferior Vena Cava Thrombus: A Rare Case Report. JCDR 2024. doi:10.7860\/JCDR\/2024\/70820.19640","DOI":"10.7860\/JCDR\/2024\/70820.19640"},{"key":"2026092401400761000_19.9.e271512.3","doi-asserted-by":"crossref","first-page":"S267","DOI":"10.4103\/0973-1482.181170","article-title":"Primary renal synovial sarcoma: A case report and literature review","volume":"14","author":"Huang","year":"2018","journal-title":"J Cancer Res Ther"},{"key":"2026092401400761000_19.9.e271512.4","first-page":"152","article-title":"Primary Renal Synovial Sarcoma: An Oncologic Surprise","volume":"2","author":"Moorthy","year":"2014","journal-title":"Urol Case Rep"},{"key":"2026092401400761000_19.9.e271512.5","doi-asserted-by":"crossref","first-page":"238","DOI":"10.5858\/2005-129-238-PRSSCB","article-title":"Primary renal synovial sarcoma confirmed by cytogenetic analysis: a lesion distinct from sarcomatoid renal cell carcinoma","volume":"129","author":"Shannon","year":"2005","journal-title":"Arch Pathol Lab Med"},{"key":"2026092401400761000_19.9.e271512.6","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.hoc.2023.04.019","article-title":"Renal Cell Carcinoma of Variant Histology: Biology and Therapies","volume":"37","author":"Msaouel","year":"2023","journal-title":"Hematol Oncol Clin North Am"},{"key":"2026092401400761000_19.9.e271512.7","first-page":"2241","article-title":"Primary synovial sarcoma of the kidney-A case report and literature review","volume":"11","author":"Tranesh","year":"2018","journal-title":"Int J Clin Exp Pathol"},{"key":"2026092401400761000_19.9.e271512.8","doi-asserted-by":"crossref","DOI":"10.3390\/jpm12091450","article-title":"Primary Synovial Sarcoma of the Kidney: Diagnostic Approach and Therapeutic Modalities for a Rare Nosological Entity","volume":"12","author":"Mastoraki","year":"2022","journal-title":"J Pers Med"},{"key":"2026092401400761000_19.9.e271512.9","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200008000-00006"},{"key":"2026092401400761000_19.9.e271512.10","doi-asserted-by":"crossref","unstructured":"Abbas M , Majeed MA , Liaqat M , et al . Primary Renal Synovial Sarcoma: A Rare Case Presentation. Cureus 2024;PMCID. doi:10.7759\/cureus.72256","DOI":"10.7759\/cureus.72256"},{"key":"2026092401400761000_19.9.e271512.11","article-title":"Primary renal synovial sarcoma","volume":"2011","author":"Gulum","year":"2011","journal-title":"Case Rep Urol"},{"key":"2026092401400761000_19.9.e271512.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.07.006"},{"key":"2026092401400761000_19.9.e271512.13","doi-asserted-by":"crossref","first-page":"498","DOI":"10.6004\/jnccn.2025.0058","article-title":"NCCN Guidelines\u00ae Insights: Soft Tissue Sarcoma, Version 1.2025","volume":"23","author":"von Mehren","year":"2025","journal-title":"J Natl Compr Canc Netw"},{"key":"2026092401400761000_19.9.e271512.14","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1200\/JCO.2017.75.1941","article-title":"Synovial Sarcoma: Current Concepts and Future Perspectives","volume":"36","author":"Stacchiotti","year":"2018","journal-title":"J Clin Oncol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-271512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:40:14Z","timestamp":1790239214000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-271512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":14,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9,24]]},"published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1136\/bcr-2025-271512"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-271512","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]}}}