{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:59:59Z","timestamp":1776697199116,"version":"3.51.2"},"reference-count":15,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,3,27]]},"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>Beh\u00e7et\u2019s disease (BD) is a rare vasculitis characterised by mucocutaneous lesions and ocular, vascular and neurological manifestations. We report a man in his early 20s who presented with dyspnoea, haemoptysis, pulmonary arterial thromboses and a large right ventricular thrombus. Initial investigations for infectious and autoimmune causes were negative, complicating diagnosis. A revisited history and new examination revealed oral and genital aphthosis, fulfilling the international criteria for BD. The patient was treated with anticoagulation and high-dose immunosuppression, resulting in rapid clinical improvement and resolution of the intracardiac thrombus. This case highlights the diagnostic challenge of BD when vascular manifestations precede recognition of the more characteristic features of BD and emphasises the therapeutic challenges of long-term secondary prevention.<\/jats:p>","DOI":"10.1136\/bcr-2025-271721","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:20:46Z","timestamp":1776694846000},"page":"e271721","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Intracardiac and pulmonary arterial thrombosis as a first presentation of Beh\u00e7et\u2019s disease"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2321-5683","authenticated-orcid":false,"given":"Katie","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Cardiology, University Hospitals of Leicester NHS Trust, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7647-4833","authenticated-orcid":false,"given":"Iyare","family":"Nehikhare","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospitals of Leicester NHS Trust, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salamat","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospitals of Leicester NHS Trust, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riyaz","family":"Somani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospitals of Leicester NHS Trust, Leicester, UK"},{"name":"Division of Cardiovascular Sciences, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"2026042007201245000_19.4.e271721.1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2016.1205486"},{"key":"2026042007201245000_19.4.e271721.2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0039.1999.540301.x"},{"key":"2026042007201245000_19.4.e271721.3","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.berh.2016.08.002","article-title":"Beh\u00e7et\u2019s disease: How to diagnose and treat vascular involvement","volume":"30","author":"Seyahi","year":"2016","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"2026042007201245000_19.4.e271721.4","doi-asserted-by":"crossref","unstructured":"Atalar E . 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A Mini Review","volume":"8","author":"K\u00f6tter","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"2026042007201245000_19.4.e271721.9","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/jdv.12107","article-title":"The International Criteria for Beh\u00e7et\u2019s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria","volume":"28","author":"Davatchi","year":"2014","journal-title":"Acad Dermatol Venereol"},{"key":"2026042007201245000_19.4.e271721.10","volume-title":"Clinical infectious diseases: An official publication of the infectious diseases society of America","volume":"77","author":"Fowler","year":"2023"},{"key":"2026042007201245000_19.4.e271721.11","doi-asserted-by":"crossref","DOI":"10.1186\/s13256-021-02931-1","article-title":"Pulmonary artery thrombosis as the first presentation of Beh\u00e7et\u2019s syndrome: a case report and review of the literature","volume":"15","author":"Alakkas","year":"2021","journal-title":"J Med Case Rep"},{"key":"2026042007201245000_19.4.e271721.12","doi-asserted-by":"crossref","first-page":"337","DOI":"10.5578\/tt.69502","article-title":"Behcet\u2019s disease presenting with pulmonary thromboembolism","volume":"68","author":"Abuzaina","year":"2020","journal-title":"Tuberk Toraks"},{"key":"2026042007201245000_19.4.e271721.13","first-page":"e95364","article-title":"Beh\u00e7et\u2019s Disease Presenting With Large Intracavitary Thrombi and Pulmonary Embolism","volume":"17","author":"Rinath","year":"2025","journal-title":"Cureus"},{"key":"2026042007201245000_19.4.e271721.14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.6.2243"},{"key":"2026042007201245000_19.4.e271721.15","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-007-0685-z"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-271721","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:20:53Z","timestamp":1776694853000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-271721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4,20]]},"published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1136\/bcr-2025-271721"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-271721","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}