{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:59:49Z","timestamp":1776697189742,"version":"3.51.2"},"reference-count":6,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,3,27]]},"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>We report a spontaneously conceived dichorionic diamniotic twin pregnancy in which a complete hydatidiform mole co-existed with a structurally normal fetus. An early ultrasound scan demonstrated a viable fetus with an adjacent cystic area initially interpreted as subchorionic haemorrhage. A definitive diagnosis was established at 21 weeks\u2019 gestation when repeat ultrasound scan revealed a separate sac containing diffuse vesicular placental tissue consistent with a complete molar co-twin.<\/jats:p>\n                  <jats:p>Although serum \u03b2-human chorionic gonadotropin (\u03b2-hCG) was elevated (236,580 mIU\/mL), this value falls within the physiological range described in twin pregnancies. The diagnosis was based primarily on ultrasound scan findings rather than biochemical parameters.<\/jats:p>\n                  <jats:p>After multidisciplinary counselling, medical termination was performed, followed by ultrasound-guided suction evacuation. Recovery was uncomplicated, with rapid regression of \u03b2-hCG levels.<\/jats:p>","DOI":"10.1136\/bcr-2025-271801","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:20:50Z","timestamp":1776694850000},"page":"e271801","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Complete hydatidiform mole with a co-existing normal fetus at mid-trimester in a dichorionic diamniotic gestation"],"prefix":"10.1136","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9941-6410","authenticated-orcid":false,"given":"Catherine Preethi","family":"D","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology, Father Muller Medical College, Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joylene Diana","family":"D\u2019Almeida","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Father Muller Medical College, Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Father Muller Medical College, Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diya","family":"Mathen","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Father Muller Medical College, Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"2026042007201013000_19.4.e271801.1","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1056\/NEJMcp0900696","article-title":"Clinical practice","volume":"360","author":"Berkowitz","year":"2009","journal-title":"Molar Pregnancy N Engl J Med"},{"key":"2026042007201013000_19.4.e271801.2","first-page":"130","article-title":"Outcome of twin pregnancies with complete hydatidiform mole and healthy co-twin","volume":"109","author":"Sebire","year":"2002","journal-title":"BJOG"},{"key":"2026042007201013000_19.4.e271801.3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ygyno.2005.02.002","article-title":"Twin pregnancy consisting of a complete hydatidiform mole and co-existing fetus: report of two cases and review of literature","volume":"98","author":"Vaisbuch","year":"2005","journal-title":"Gynecol Oncol"},{"key":"2026042007201013000_19.4.e271801.4","doi-asserted-by":"publisher","DOI":"10.1080\/00016340701415236"},{"key":"2026042007201013000_19.4.e271801.5","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/uog.11960","article-title":"P14.10: Massive necrosis of complete hydatidiform mole in a twin pregnancy with coexisting fetus","volume":"40","author":"Francisco","year":"2012","journal-title":"Ultrasound in Obstet & Gyne"},{"key":"2026042007201013000_19.4.e271801.6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/uog.11961","article-title":"P14.11: Prenatal diagnosis and management of an ICSI twin pregnancy complicated by a co\u2010existing molar pregnancy","volume":"40","author":"Tan","year":"2012","journal-title":"Ultrasound in Obstet & Gyne"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-271801","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:20:56Z","timestamp":1776694856000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-271801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4,20]]},"published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1136\/bcr-2025-271801"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-271801","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}