{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T14:03:59Z","timestamp":1784642639579,"version":"3.55.0"},"reference-count":12,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2026,7,5]]},"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>Bartter syndrome, a rare autosomal recessive disorder (1 in 1\u2009000\u2009000), causes salt wasting due to defects in the ion channels of the loop of Henle. In this case report, a young adolescent girl, who is a known case of Bartter syndrome and a recognised endosulfan exposure victim, presented with sensorineural hearing loss and multiple episodes of vomiting. She was treated with intravenous fluids, potassium supplementation and indomethacin. This case highlights the importance of early recognition and routine biochemical investigations to prevent complications of inherited tubulopathies.<\/jats:p>","DOI":"10.1136\/bcr-2025-271920","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T13:35:35Z","timestamp":1784640935000},"page":"e271920","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Rare confluence: clinically diagnosed Bartter syndrome with sensorineural hearing loss in a young endosulfan-exposed patient"],"prefix":"10.1136","volume":"19","author":[{"given":"Samika","family":"Jhawar","sequence":"first","affiliation":[{"name":"Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7357-3772","authenticated-orcid":false,"given":"Rukmini","family":"Mysore Srikantiah","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swayam","family":"Adappa","sequence":"additional","affiliation":[{"name":"Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayathri","family":"Renganathan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamalakshi G","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,7,21]]},"reference":[{"key":"2026072106351652000_19.7.e271920.1","unstructured":"Bokhari SRA , Zulfiqar H , Mansur A . Bartter syndrome statPearls - NCBI bookshelf. 2023. Available: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK442019\/"},{"key":"2026072106351652000_19.7.e271920.2","doi-asserted-by":"crossref","DOI":"10.3390\/medicina59091638","article-title":"Bartter Syndrome: A Systematic Review of Case Reports and Case Series","volume":"59","author":"Qasba","year":"2023","journal-title":"Medicina (Kaunas)"},{"key":"2026072106351652000_19.7.e271920.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.10.035"},{"key":"2026072106351652000_19.7.e271920.4","unstructured":"Department of Health and Family Welfare, Government of Kerala . Endosulfan the Kerala story: report on the health effects of endosulfan and progress of rehabilitation activities in Kerala. Government of Kerala, India; 2011. Available: https:\/\/www.cseindia.org\/report-on-health-effects-of-endosulfan-and-progress-of-rehabilitation-activities-in-kerala-by-govt-of-kerala-7676 [Accessed 29 Mar 2026]."},{"key":"2026072106351652000_19.7.e271920.5","unstructured":"Orphanet: bartter syndrome type 4. Available: https:\/\/www.orpha.net\/en\/disease\/detail\/89938# [Accessed 29 Mar 2026]."},{"key":"2026072106351652000_19.7.e271920.6","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008010102"},{"key":"2026072106351652000_19.7.e271920.7","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004667","article-title":"Electrophysiology of Hypokalemia and Hyperkalemia","volume":"10","author":"Weiss","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2026072106351652000_19.7.e271920.8","unstructured":"Frassetto LAMD . Bartter syndrome: practice essentials, pathophysiology, etiology. Available: https:\/\/emedicine.medscape.com\/article\/238670-overview#:~:text=Most%20recently%2C%20an%20international%20team,disappeared%20spontaneously%20during%20follow%2Dup [Accessed 29 Mar 2026]."},{"key":"2026072106351652000_19.7.e271920.9","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/pd.6508","article-title":"Successful antenatal treatment of MAGED2-related Bartter syndrome and review of treatment options and efficacy","volume":"44","author":"Walsh","year":"2024","journal-title":"Prenat Diagn"},{"key":"2026072106351652000_19.7.e271920.10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.5662\/wjm.v5.i2.55","article-title":"Bartter and Gitelman syndromes: Spectrum of clinical manifestations caused by different mutations","volume":"5","author":"Shibli","year":"2015","journal-title":"WJM"},{"key":"2026072106351652000_19.7.e271920.11","doi-asserted-by":"crossref","DOI":"10.1210\/jendso\/bvac079","article-title":"The Bartter-Gitelman Spectrum: 50-Year Follow-up With Revision of Diagnosis After Whole-Genome Sequencing","volume":"6","author":"Stevenson","year":"2022","journal-title":"J Endocr Soc"},{"key":"2026072106351652000_19.7.e271920.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jflm.2017.07.008"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2025-271920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T13:35:44Z","timestamp":1784640944000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2025-271920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":12,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,7,21]]},"published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1136\/bcr-2025-271920"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2025-271920","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]}}}